Metronidazole and Hyperaesthesia - a phase IV clinical study of FDA data

Summary:

Hyperaesthesia is reported as a side effect among people who take Metronidazole (metronidazole), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Lipitor, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperaesthesia when taking Metronidazole. It is created by eHealthMe based on reports of 58,146 people who have side effects when taking Metronidazole from the FDA, and is updated regularly.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

What is Hyperaesthesia?

Hyperaesthesia is found to be associated with 829 drugs and 917 conditions by eHealthMe. Check the latest studies of Hyperaesthesia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

58,146 people reported to have side effects when taking Metronidazole.
Among them, 55 people (0.09%) have Hyperaesthesia.

Could Metronidazole cause Hyperaesthesia?

Among these 55 people:

How long have people been on Metronidazole when they have Hyperaesthesia? *

What is the gender of people who have Hyperaesthesia when taking Metronidazole? *

female: 67.44 %
male: 32.56 %

What is the age of people who have Hyperaesthesia when taking Metronidazole? *

What are other drugs people take besides Metronidazole? *

Lipitor: 16 people, 29.09%
Zometa: 10 people, 18.18%
Aredia: 10 people, 18.18%
Femara: 10 people, 18.18%
Gabapentin: 9 people, 16.36%
Acetaminophen And Hydrocodone Bitartrate: 8 people, 14.55%
Vancomycin: 8 people, 14.55%
Paroxetine Hydrochloride: 8 people, 14.55%
Soma: 7 people, 12.73%
Bisoprolol Fumarate And Hydrochlorothiazide: 7 people, 12.73%

What are other side effects people have besides Hyperaesthesia? *

Fever: 25 people, 45.45%
Rashes (redness): 22 people, 40.00%
Diarrhea: 16 people, 29.09%
Pain: 16 people, 29.09%
Fatigue (feeling of tiredness): 14 people, 25.45%
Dizziness: 13 people, 23.64%
Headache (pain in head): 12 people, 21.82%
Feeling Abnormal: 12 people, 21.82%
Urination - Painful: 12 people, 21.82%
Injury: 11 people, 20.00%

What are the existing conditions these people have? *

Primary Myelofibrosis (primary disorder of the bone marrow): 8 people, 14.55%
High Blood Pressure: 8 people, 14.55%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 7 people, 12.73%
Pain: 7 people, 12.73%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 7 people, 12.73%
High Blood Cholesterol: 6 people, 10.91%
Diarrhea: 5 people, 9.09%
Anaemia (lack of blood): 4 people, 7.27%
Headache (pain in head): 4 people, 7.27%
Pneumonia: 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

Do you take Metronidazole and have Hyperaesthesia?

- Check whether Hyperaesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metronidazole:

Metronidazole (59,578 reports)

Hyperaesthesia treatments and more:

Hyperaesthesia (10,827 reports)

Browse all side effects of Metronidazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperaesthesia:

Hyperaesthesia (829 drugs)

Browse all the conditions that are associated with Hyperaesthesia:

Hyperaesthesia (917 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole (the active ingredients of Metronidazole) and Metronidazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.