Memantine and Zoledronic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Memantine (memantine) and Zoledronic acid (zoledronic acid). Common drug interactions include dry skin among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Memantine and Zoledronic acid. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Memantine?

Memantine has active ingredients of memantine. It is often used in alzheimer's disease. eHealthMe is studying from 10,266 Memantine users. Check the latest studies of Memantine.

What is Zoledronic acid?

Zoledronic acid has active ingredients of zoledronic acid. eHealthMe is studying from 28,485 Zoledronic acid users. Check the latest studies of Zoledronic acid.



On Jul, 15, 2026

14 people who take Memantine and Zoledronic acid together, and have interactions are studied.

Memantine and Zoledronic acid drug interactions.

What are the common drug interactions of Memantine and Zoledronic Acid, by gender? *:

female:

  1. Dry skin
  2. Dyspnoea (difficult or laboured respiration)
  3. Flushing (the warm, red condition of human skin)
  4. Headache (pain in head)
  5. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  6. Myalgia (muscle pain)
  7. Nausea (feeling of having an urge to vomit)
  8. Neck pain
  9. Skin warm
  10. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)

male:

  1. Pneumonia
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Herpes zoster
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pain

What are the common drug interactions of Memantine and Zoledronic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Pneumonia

50-59:

n/a

60+:

  1. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  2. Anxiety
  3. Myalgia (muscle pain)
  4. Nausea (feeling of having an urge to vomit)
  5. Neck pain
  6. Skin warm
  7. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)
  9. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
  10. Tremor (trembling or shaking movements in one or more parts of your body)

What are the existing conditions these people have? *

  1. Osteoporosis (bones weak and more likely to break): 6 people, 42.86%
  2. Multiple Myeloma (cancer of the plasma cells): 5 people, 35.71%
  3. Encephalopathy (functioning of the brain is affected by some agent or condition): 5 people, 35.71%
  4. High Blood Pressure: 5 people, 35.71%
  5. Leukopenia (less number of white blood cells in blood): 4 people, 28.57%
  6. Blood Magnesium Decreased: 4 people, 28.57%
  7. Breast Cancer: 4 people, 28.57%
  8. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 4 people, 28.57%
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 28.57%
  10. Hypokalemia (low potassium): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Memantine and Zoledronic acid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Memantine and Zoledronic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Memantine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zoledronic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Memantine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on memantine and zoledronic acid (the active ingredients of Memantine and Zoledronic acid, respectively), and Memantine and Zoledronic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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