Mercaptopurine and Boniva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mercaptopurine (mercaptopurine) and Boniva (ibandronate sodium). Common drug interactions include eye swelling among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Mercaptopurine and Boniva. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Boniva?

Boniva has active ingredients of ibandronate sodium. It is often used in osteoporosis. eHealthMe is studying from 27,340 Boniva users. Check the latest studies of Boniva.



On Jul, 15, 2026

19 people who take Mercaptopurine and Boniva together, and have interactions are studied.

Mercaptopurine and Boniva drug interactions.

What are the common drug interactions of Mercaptopurine and Boniva, by gender? *:

female:

  1. Eye swelling
  2. Food allergy
  3. Rash
  4. Throat irritation
  5. Abortion induced (medically referred abortion)
  6. Adverse drug reaction
  7. Adverse event
  8. Alopecia (absence of hair from areas of the body)
  9. Anaemia (lack of blood)
  10. Arthralgia (joint pain)

male:

  1. Anxiety
  2. Femur fracture
  3. Oropharyngeal discomfort (pain or irritation of oropharynx)
  4. Swelling
  5. White blood cell count increased
  6. Injection site pain
  7. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  8. Abdominal pain upper
  9. Blood potassium decreased
  10. Diarrhoea

What are the common drug interactions of Mercaptopurine and Boniva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Anxiety
  2. Femur fracture
  3. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  4. Abdominal pain upper
  5. Blood potassium decreased
  6. Diarrhoea
  7. Gastric disorder (disease of stomach)
  8. Joint swelling
  9. Swelling
  10. White blood cell count increased

20-29:

  1. Abortion induced (medically referred abortion)
  2. Adverse drug reaction
  3. Adverse event
  4. Alopecia (absence of hair from areas of the body)
  5. Anaemia (lack of blood)
  6. Arthralgia (joint pain)
  7. Back pain
  8. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  9. Cerumen impaction
  10. Eye disorder

30-39:

  1. Eye swelling
  2. Food allergy
  3. Rash
  4. Throat irritation

40-49:

  1. Hepatic enzyme increased
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

  1. Injection site pain
  2. Bone loss
  3. Fatigue (feeling of tiredness)
  4. Ill-defined disorder
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Weight decreased

60+:

  1. Catheter site infection (infection at the site of insertion)
  2. Cough
  3. Pelvic abscess
  4. Postoperative wound infection
  5. Sinusitis (inflammation of sinus)
  6. Skin reaction
  7. Cystitis (inflammation of the wall of the bladder)
  8. Device related infection
  9. Diarrhoea
  10. Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)

What are the existing conditions these people have? *

  1. Urinary Tract Infection: 2 people, 10.53%
  2. Sleep Disorder: 2 people, 10.53%
  3. Pain: 2 people, 10.53%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 2 people, 10.53%
  5. Nausea (feeling of having an urge to vomit): 2 people, 10.53%
  6. Muscle Spasms (muscle contraction): 2 people, 10.53%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
  8. Depression: 2 people, 10.53%
  9. Birth Control: 2 people, 10.53%
  10. Anaemia (lack of blood): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

Do you take Mercaptopurine and Boniva?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mercaptopurine and Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mercaptopurine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Boniva:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mercaptopurine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Boniva and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mercaptopurine and ibandronate sodium (the active ingredients of Mercaptopurine and Boniva, respectively), and Mercaptopurine and Boniva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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