Mercaptopurine and Doxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mercaptopurine (mercaptopurine) and Doxil (doxorubicin hydrochloride). Common drug interactions include febrile neutropenia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Mercaptopurine and Doxil. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Mercaptopurine?

Mercaptopurine has active ingredients of mercaptopurine. It is often used in crohn's disease. eHealthMe is studying from 23,013 Mercaptopurine users. Check the latest studies of Mercaptopurine.

What is Doxil?

Doxil has active ingredients of doxorubicin hydrochloride. It is often used in ovarian cancer. eHealthMe is studying from 10,479 Doxil users. Check the latest studies of Doxil.

On Jul, 08, 2026

27 people who take Mercaptopurine and Doxil together, and have interactions are studied.

Mercaptopurine and Doxil drug interactions.

What are the common drug interactions of Mercaptopurine and Doxil, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Pneumonia fungal
Rhinovirus infection
Viral upper respiratory tract infection
Epistaxis (bleed from the nose)
Fungal infection
Haematochezia (passage of stools containing blood)
Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina)
Neutropenic colitis (inflammation of the cecum, often with involvement of the ascending colon and ileum, a life threatening condition)

male:

Febrile neutropenia (fever with reduced white blood cells)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Streptococcal infection
Lentigo (a small pigmented spot on the skin with a clearly-defined edge, surrounded by normal-appearing skin)
Rash
Sepsis (a severe blood infection that can lead to organ failure and death)
Hypertension (high blood pressure)
Lower respiratory tract infection fungal
Upper respiratory tract infection
Vomiting

What are the common drug interactions of Mercaptopurine and Doxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pertussis (whooping cough: a disease of the respiratory mucous membrane)
Anaemia (lack of blood)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Neutropenia (an abnormally low number of neutrophils)
Platelet count decreased
Pyrexia (fever)
Streptococcal infection
Febrile neutropenia (fever with reduced white blood cells)
Lentigo (a small pigmented spot on the skin with a clearly-defined edge, surrounded by normal-appearing skin)

10-19:

Febrile neutropenia (fever with reduced white blood cells)
Pneumonia fungal
Anaemia (lack of blood)
Hypertension (high blood pressure)
Lower respiratory tract infection fungal
Pancreatitis (inflammation of pancreas)
Upper respiratory tract infection
Rhinovirus infection
Viral upper respiratory tract infection
Colitis (inflammation of colon)

20-29:

Nausea (feeling of having an urge to vomit)
Febrile neutropenia (fever with reduced white blood cells)
Pancreatitis (inflammation of pancreas)
Vomiting
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
Torsade de pointes (a abnormal heart rate with abnormal beating pattern)
Ventricular fibrillation (abnormally irregular heart rhythm)

30-39:

Bacterial infection
Septic shock (shock due to blood infection)
Strongyloidiasis (infection with strongyloides stercoralis)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Enterovirus infection
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Meningitis enterococcal (fungal inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Pleocytosis (increased cell count)
Pneumonia fungal
Pneumonia viral

40-49:

Febrile neutropenia (fever with reduced white blood cells)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 16 people, 59.26%
B Precursor Type Acute Leukaemia (lymphoid cancer): 7 people, 25.93%
Nausea (feeling of having an urge to vomit): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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