Meropenem and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Meropenem (meropenem) and Divalproex (divalproex sodium). Common drug interactions include lung neoplasm among females and overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Meropenem and Divalproex. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Meropenem?

Meropenem has active ingredients of meropenem. eHealthMe is studying from 33,295 Meropenem users. Check the latest studies of Meropenem.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 18, 2026

34 people who take Meropenem and Divalproex together, and have interactions are studied.

Meropenem and Divalproex drug interactions.

What are the common drug interactions of Meropenem and Divalproex, by gender? *:

female:

Lung neoplasm (tumour of lung)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Nausea (feeling of having an urge to vomit)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Osteoporosis (bones weak and more likely to break)
Platelet count decreased
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory rate increased (excess breathing rate/min)

male:

Overdose
Hypotension (abnormally low blood pressure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Unresponsive to stimuli
Coma (state of unconsciousness lasting more than six hours)
Drug level below therapeutic
Acute respiratory failure
Anticonvulsant drug level below therapeutic

What are the common drug interactions of Meropenem and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Drug ineffective
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Unresponsive to stimuli

20-29:

Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Cystic fibrosis pancreatic (fibrosis with cyst in the pancreas)
Cystic fibrosis related diabetes
Drug level below therapeutic
Infective exacerbation of bronchiectasis (severe infective lung disease)
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Mycobacterium abscessus infection (rapid growing bacterial infection)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pancreatic insufficiency
Post procedural pneumonia

30-39:

Anxiety
Heart rate increased
Hyperhidrosis (abnormally increased sweating)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
Respiratory rate increased (excess breathing rate/min)
Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
Suicide attempt

40-49:

Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Overdose
Unresponsive to stimuli
Confusional state
Drug level decreased
Drug level increased
Dysphagia (a condition in which swallowing is difficult or painful)
Hyperammonaemia
Nervous system disorder (a general class of medical conditions affecting the nervous system)
Oropharyngeal pain

50-59:

Hypotension (abnormally low blood pressure)
Pneumonia
Aspergillosis (an infection caused by a fungus called aspergillus)
Hypernatraemia (an abnormally high plasma concentration of sodium ions)
Lung infection
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Acute respiratory failure
Anticonvulsant drug level below therapeutic

60+:

Bacterial infection
Febrile neutropenia (fever with reduced white blood cells)
Clostridium test positive
Pain
Renal cancer (cancer of kidney)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Cerebral haemorrhage (bleeding within the brain)
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Pneumonia: 8 people, 23.53%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 6 people, 17.65%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 11.76%
Overdose: 3 people, 8.82%
Urinary Tract Infection: 2 people, 5.88%
Cellulitis (infection under the skin): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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