Mesna and Camptosar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesna (mesna) and Camptosar (irinotecan hydrochloride). Common drug interactions include fatigue among females and stomatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Mesna and Camptosar. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.

What is Camptosar?

Camptosar has active ingredients of irinotecan hydrochloride. eHealthMe is studying from 7,145 Camptosar users. Check the latest studies of Camptosar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

21 people who take Mesna and Camptosar together, and have interactions are studied.

Mesna and Camptosar drug interactions.

What are the common drug interactions of Mesna and Camptosar, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Back pain
  3. Death
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Vision blurred

male:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Pharyngeal inflammation
  3. Malignant neoplasm progression (cancer tumour came back)
  4. Metastases to meninges (cancer spreads to meninges)
  5. Nystagmus (a condition of involuntary eye movement)
  6. Pneumonia
  7. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  8. Pyrexia (fever)
  9. Respiratory distress (difficulty in breathing)
  10. Respiratory rate decreased (less breathing rate/min)

What are the common drug interactions of Mesna and Camptosar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  2. Anaemia (lack of blood)
  3. Thrombocytopenia (decrease of platelets in blood)
  4. Vomiting
  5. Abdominal distension
  6. Abdominal pain
  7. Angioedema (rapid swelling of the dermis)
  8. Atelectasis (partial or complete collapse of the lung)
  9. Coagulopathy (blood's ability to clot is impaired)
  10. Decreased appetite

10-19:

  1. Stomatitis (inflammation of mucous membrane of mouth)
  2. Pharyngeal inflammation
  3. Dry mouth
  4. Hypophagia (reduced food intake)
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Oral pain
  7. Oropharyngeal pain

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Rhabdomyosarcoma (cancer of the bone, soft tissues, or connective tissue (e.g., tendon or cartilage)): 8 people, 38.10%
  2. Pain: 2 people, 9.52%
  3. Nausea (feeling of having an urge to vomit): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Mesna and Camptosar?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Mesna and Camptosar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Mesna:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Camptosar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mesna and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Camptosar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on mesna and irinotecan hydrochloride (the active ingredients of Mesna and Camptosar, respectively), and Mesna and Camptosar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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