Mesna and Diazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Mesna (mesna) and Diazepam (diazepam). Common drug interactions include hyperhidrosis among females and pulmonary hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Mesna and Diazepam. It is created by eHealthMe based on reports of 58 people who take the same drugs from the FDA, and is updated regularly.

What is Mesna?

Mesna has active ingredients of mesna. eHealthMe is studying from 9,647 Mesna users. Check the latest studies of Mesna.

What is Diazepam?

Diazepam has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 108,384 Diazepam users. Check the latest studies of Diazepam.

On Jul, 14, 2026

58 people who take Mesna and Diazepam together, and have interactions are studied.

What are the common drug interactions of Mesna and Diazepam, by gender? *:

female:

Hyperhidrosis (abnormally increased sweating)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Incoherent (talking in a confused and unclear way)
Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
Migraine (headache)
Myocarditis (inflammation of heart muscle myocardium)
Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
Oral disorder (mouth disease)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)

male:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
Coma (state of unconsciousness lasting more than six hours)
Cough
Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Abnormal behaviour
Bacterial sepsis
Candida sepsis (candida in blood stream)
Cardiac failure

What are the common drug interactions of Mesna and Diazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Restrictive cardiomyopathy (a condition in which the walls of the lower chambers of the heart (the ventricles) are abnormally rigid and lack the flexibility)
Heart transplant

10-19:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Fatigue (feeling of tiredness)
Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries))
Mucosal inflammation (infection of mucous membrane)
Cerebral haemorrhage (bleeding within the brain)

20-29:

Febrile neutropenia (fever with reduced white blood cells)
Headache (pain in head)
Hepatomegaly (abnormal enlargement of the liver)
Hypertensive emergency
Hypotension (abnormally low blood pressure)
Incoherent (talking in a confused and unclear way)
Insomnia (sleeplessness)
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)

30-39:

Angina pectoris (chest pain due to ischemia of the heart muscle)
Bone pain
Chest pain
Febrile infection (infection with temperature rise)

40-49:

Renal failure (kidney dysfunction)
Alopecia totalis (loss of all head hair)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Aphasia (damage to the parts of the brain that control language)
Bacterial infection
Bone marrow disorder
Decreased appetite
Depression
Diarrhoea
Dizziness

50-59:

Cellulitis (infection under the skin)
Cough
Febrile neutropenia (fever with reduced white blood cells)
Neutropenia (an abnormally low number of neutrophils)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Death
Hepatomegaly (abnormal enlargement of the liver)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)

60+:

Encephalopathy (functioning of the brain is affected by some agent or condition)
Crying
Enterococcal sepsis
Gamma-glutamyltransferase increased
Granulocytopenia (lack of granulocyte)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
White blood cell count decreased
Feeling of despair
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Lymphoma (cancer that begins in immune system cells): 12 people, 20.69%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 11 people, 18.97%
Bone Marrow Conditioning Regimen: 8 people, 13.79%
Pain: 5 people, 8.62%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 8.62%
Insomnia (sleeplessness): 5 people, 8.62%
Depression: 5 people, 8.62%
Nausea (feeling of having an urge to vomit): 4 people, 6.90%
Stomatitis (inflammation of mucous membrane of mouth): 3 people, 5.17%
Hypotension (abnormally low blood pressure): 3 people, 5.17%

* Approximation only. Some reports may have incomplete information.

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