Metadate cd and Risperdal drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metadate cd (methylphenidate hydrochloride) and Risperdal (risperidone). Common drug interactions include anoxic encephalopathy among females and gynaecomastia among males.

The phase IV clinical study analyzes what interactions people have when they take Metadate cd and Risperdal. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Metadate cd?

Metadate cd has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 646 Metadate cd users. Check the latest studies of Metadate cd.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

On Jul, 06, 2026

35 people who take Metadate cd and Risperdal together, and have interactions are studied.

Metadate cd and Risperdal drug interactions.

What are the common drug interactions of Metadate Cd and Risperdal, by gender? *:

female:

Anoxic encephalopathy (brain damage due to lack of oxygen)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Ventricular fibrillation (abnormally irregular heart rhythm)
Weight increased
Asthma
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Homicidal ideation (thoughts about human killing another human)
Obesity (having too much body fat)
Suicidal ideation
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

male:

Gynaecomastia (enlargement of the gland tissue of the male breast)
Breast discharge
Type 1 diabetes mellitus
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Dyskinesia (abnormality or impairment of voluntary movement)
Obesity (having too much body fat)
Agitation (state of anxiety or nervous excitement)
Weight increased
Aphthous stomatitis (mouth ulcer)
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Metadate Cd and Risperdal, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Emotional distress
Gynaecomastia (enlargement of the gland tissue of the male breast)
Agitation (state of anxiety or nervous excitement)
Obesity (having too much body fat)
Aphthous stomatitis (mouth ulcer)
Flushing (the warm, red condition of human skin)
Gingival erythema (redness of gums)
Heart rate increased
Oral pain
Aggression

10-19:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperglycaemia (high blood sugar)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Death
Ketonuria (ketones in urine)
Type 1 diabetes mellitus
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Weight increased
Dyskinesia (abnormality or impairment of voluntary movement)
Asthma

20-29:

Anoxic encephalopathy (brain damage due to lack of oxygen)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Malaise (a feeling of general discomfort or uneasiness)
Oedema (fluid collection in tissue)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pericardial effusion (fluid around the heart)
Right ventricular dysfunction
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Oppositional Defiant Disorder (a childhood disorder described by the diagnostic and statistical manual of mental disorders): 6 people, 17.14%
Abnormal Behavior: 5 people, 14.29%
Tachyphrenia (abnormally rapid mental activity): 3 people, 8.57%
Mental Impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition): 3 people, 8.57%
Mood Swings (an extreme or rapid change in mood): 2 people, 5.71%
Irritability: 2 people, 5.71%
Astrocytoma (tumour of the brain that originate in a particular kind of glial-cells): 2 people, 5.71%
Asthma: 2 people, 5.71%
Anger: 2 people, 5.71%
Affective Disorder (mental disorder): 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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