Metformin and Astragalus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Astragalus (astragalus). Common drug interactions include anaemia among females and aphasia among males.
The phase IV clinical study analyzes what interactions people have when they take Metformin and Astragalus. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.
What is Astragalus?
Astragalus has active ingredients of astragalus. eHealthMe is studying from 427 Astragalus users. Check the latest studies of Astragalus.
19 people who take Metformin and Astragalus together, and have interactions are studied.

What are the common drug interactions of Metformin and Astragalus, by gender? *:
female:
- Anaemia (lack of blood)
- Blood glucose increased
- Renal disorder (kidney disease)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
- Abdominal mass (localized enlargement or swelling in the human abdomen)
- Blood urea increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dehydration (dryness resulting from the removal of water)
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Drug hypersensitivity
male:
- Aphasia (damage to the parts of the brain that control language)
- Arthralgia (joint pain)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Joint swelling
- Neuropathy peripheral (surface nerve damage)
- Pain in extremity
- Pancreatic disorder
- Parasite blood test positive
- Peripheral swelling
- Pyrexia (fever)
What are the common drug interactions of Metformin and Astragalus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Death
- Pneumonia
30-39:
n/a
40-49:
n/a
50-59:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Fatigue (feeling of tiredness)
- Injection site pain
60+:
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Fatigue (feeling of tiredness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Joint swelling
- Neuropathy peripheral (surface nerve damage)
- Pain in extremity
- Pancreatic disorder
- Parasite blood test positive
- Peripheral swelling
What are the existing conditions these people have? *
- Type 2 Diabetes: 5 people, 26.32%
- Anaemia (lack of blood): 3 people, 15.79%
- Urination - Excessive Volume: 3 people, 15.79%
- Urinary Tract Infection: 3 people, 15.79%
- Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 3 people, 15.79%
- Cystic Fibrosis (disease of the secretary glands): 3 people, 15.79%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 15.79%
- Hypoglycemia (low blood sugar): 3 people, 15.79%
- Hypotension (abnormally low blood pressure): 3 people, 15.79%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 3 people, 15.79%
* Approximation only. Some reports may have incomplete information.
Do you take Metformin and Astragalus?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Metformin (465,354 reports)
- Astragalus (427 reports)
Browse all drug interactions of Metformin and Astragalus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Metformin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Astragalus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metformin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Astragalus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride and astragalus (the active ingredients of Metformin and Astragalus, respectively), and Metformin and Astragalus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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