Edurant and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Edurant (rilpivirine hydrochloride) and Metformin (metformin hydrochloride). Common drug interactions include renal pain among females and aggression among males.

The phase IV clinical study analyzes what interactions people have when they take Edurant and Metformin. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Edurant?

Edurant has active ingredients of rilpivirine hydrochloride. eHealthMe is studying from 2,238 Edurant users. Check the latest studies of Edurant.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 12, 2026

85 people who take Edurant and Metformin together, and have interactions are studied.

Edurant and Metformin drug interactions.

What are the common drug interactions of Edurant and Metformin, by gender? *:

female:

Renal pain (kidney pain)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Abdominal pain upper
Bone density decreased
Depression
Diarrhoea
Dyspepsia (indigestion)
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)

male:

Aggression
Psychotic disorder
Osteopenia (a condition where bone mineral density is lower than normal)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Tooth loss
Depressed mood
Osteoporosis (bones weak and more likely to break)
Bone density decreased
Bone loss

What are the common drug interactions of Edurant and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Anxiety
Emotional distress
Pain
Chronic kidney disease
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Psychotic behaviour
Blood triglycerides increased
Osteonecrosis (death of bone)
Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)

50-59:

Weight increased
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Headache (pain in head)
Muscle rupture (tear in muscle)
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)

60+:

Headache (pain in head)
Depressed mood
Bone density decreased
Bone loss
Emotional distress
Foot fracture
Multiple fractures
Osteonecrosis (death of bone)
Pain
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Hiv Infection: 79 people, 92.94%
High Blood Cholesterol: 40 people, 47.06%
Stress And Anxiety: 36 people, 42.35%
Sleep Disorder: 36 people, 42.35%
Blood Pressure Abnormal: 35 people, 41.18%
Psychotic Disorder: 35 people, 41.18%
Affective Disorder (mental disorder): 33 people, 38.82%
Weight Decreased: 28 people, 32.94%
High Blood Pressure: 15 people, 17.65%
Enlarged Prostate: 7 people, 8.24%

* Approximation only. Some reports may have incomplete information.

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