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Metformin and Ellence drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Ellence (epirubicin hydrochloride). Common drug interactions include alopecia among females.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Ellence. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Ellence?

Ellence has active ingredients of epirubicin hydrochloride. eHealthMe is studying from 943 Ellence users. Check the latest studies of Ellence.

On Jul, 08, 2026

40 people who take Metformin and Ellence together, and have interactions are studied.

Metformin and Ellence drug interactions.

What are the common drug interactions of Metformin and Ellence, by gender? *:

female:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Nausea (feeling of having an urge to vomit)
  4. Productive cough
  5. Psychological trauma
  6. Emotional distress
  7. Hair disorder
  8. Anxiety
  9. Pain
  10. Alopecia areata (patchy baldness that typically begins with rapid hair loss)

male:

n/a

What are the common drug interactions of Metformin and Ellence, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Alopecia (absence of hair from areas of the body)

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Hair colour changes
  3. Hair disorder
  4. Anxiety
  5. Psychological trauma
  6. Emotional distress
  7. Pain

50-59:

  1. Alopecia areata (patchy baldness that typically begins with rapid hair loss)
  2. Diarrhoea
  3. Emotional distress
  4. Gastroenteritis (inflammation of stomach and intestine)
  5. Nausea (feeling of having an urge to vomit)
  6. Productive cough
  7. Anxiety
  8. Hair disorder
  9. Alopecia (absence of hair from areas of the body)
  10. Psychological trauma

60+:

  1. Alopecia (absence of hair from areas of the body)
  2. Emotional distress
  3. Anxiety
  4. Psychological trauma
  5. Hair colour changes
  6. Hair disorder
  7. Pain

What are the existing conditions these people have? *

  1. Breast Cancer Female: 28 people, 70.00%
  2. Breast Cancer Metastatic: 5 people, 12.50%
  3. Breast Cancer: 4 people, 10.00%
  4. Pain: 2 people, 5.00%
  5. Constipation: 2 people, 5.00%
  6. Breast Cancer Stage Iii: 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and Ellence?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Metformin and Ellence:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ellence:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metformin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ellence and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride and epirubicin hydrochloride (the active ingredients of Metformin and Ellence, respectively), and Metformin and Ellence (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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