Metformin and Gadavist drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Gadavist (gadobutrol). Common drug interactions include anaphylactic reaction among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Gadavist. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Gadavist?

Gadavist has active ingredients of gadobutrol. eHealthMe is studying from 3,726 Gadavist users. Check the latest studies of Gadavist.

On Apr, 27, 2026

15 people who take Metformin and Gadavist together, and have interactions are studied.

Metformin and Gadavist drug interactions.

What are the common drug interactions of Metformin and Gadavist, by gender? *:

female:

Anaphylactic reaction (serious allergic reaction)
Cough
Dyspnoea (difficult or laboured respiration)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Premature baby
Pruritus (severe itching of the skin)
Blood creatinine increased

male:

Headache (pain in head)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Colonoscopy
Cough
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Hyperhidrosis (abnormally increased sweating)

What are the common drug interactions of Metformin and Gadavist, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood creatinine increased
Glomerular filtration rate decreased

30-39:

n/a

40-49:

Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Premature baby
Urticaria (rash of round, red welts on the skin that itch intensely)
Blood pressure decreased
Eye swelling
Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
Syncope (loss of consciousness with an inability to maintain postural tone)
Throat irritation

50-59:

Anaphylactic reaction (serious allergic reaction)
Cough
Dyspnoea (difficult or laboured respiration)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Wheezing (a high-pitched whistling sound made while you breath)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chest pain
Arthralgia (joint pain)
Bone pain
Burning sensation

60+:

Urticaria (rash of round, red welts on the skin that itch intensely)
Anaphylactic reaction (serious allergic reaction)
Tinnitus (a ringing in the ears)
Arthralgia (joint pain)
Cold sweat
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Headache (pain in head)
Hyperhidrosis (abnormally increased sweating)

What are the existing conditions these people have? *

Type 2 Diabetes: 2 people, 13.33%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 13.33%
High Blood Pressure: 2 people, 13.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 6.67%
Chest Pain: 1 person, 6.67%
Constipation: 1 person, 6.67%
Depression: 1 person, 6.67%
Diarrhea: 1 person, 6.67%
Dizziness: 1 person, 6.67%
Hormone Level Abnormal: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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