Metformin and Ganciclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Ganciclovir (ganciclovir). Common drug interactions include neutropenia among females and pulmonary embolism among males.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Ganciclovir. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

What is Ganciclovir?

Ganciclovir has active ingredients of ganciclovir. eHealthMe is studying from 6,370 Ganciclovir users. Check the latest studies of Ganciclovir.



On Jul, 13, 2026

46 people who take Metformin and Ganciclovir together, and have interactions are studied.

Metformin and Ganciclovir drug interactions.

What are the common drug interactions of Metformin and Ganciclovir, by gender? *:

female:

  1. Neutropenia (an abnormally low number of neutrophils)
  2. Pneumonia
  3. Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  7. Urinary tract infection
  8. Bacterial infection
  9. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  10. Cytomegalovirus infection

male:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Asthenia (weakness)
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  5. Arthralgia (joint pain)
  6. Blood creatine phosphokinase increased
  7. Dyspnoea (difficult or laboured respiration)
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  9. Myalgia (muscle pain)
  10. Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Metformin and Ganciclovir, by age (0-1 to 60+)? *:

0-1:

  1. Hypoglycaemia (deficiency of glucose in the bloodstream)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chest discomfort
  2. Decreased appetite
  3. Depression
  4. Drug ineffective
  5. Dry eye (lack of adequate tears)
  6. Dry skin
  7. Dyspnoea (difficult or laboured respiration)
  8. Eye disorder
  9. Fatigue (feeling of tiredness)
  10. Gastric disorder (disease of stomach)

40-49:

  1. Bacterial infection
  2. Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
  3. Cytomegalovirus infection
  4. Diabetes mellitus inadequate control
  5. Interstitial lung disease
  6. Dehydration (dryness resulting from the removal of water)
  7. Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)

50-59:

  1. Dizziness
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Asthenia (weakness)
  5. Delirium (wild excitement)
  6. Diarrhoea
  7. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough)
  8. Neutropenia (an abnormally low number of neutrophils)
  9. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  10. Cardiac failure

60+:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Respiratory failure (inadequate gas exchange by the respiratory system)
  3. Muscular weakness (muscle weakness)
  4. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  5. Alveolitis (inflammation in the socket of a tooth)
  6. Candiduria (candida in urine)
  7. Diarrhoea
  8. Inappropriate antidiuretic hormone secretion
  9. Interstitial lung disease
  10. Oedema (fluid collection in tissue)

What are the existing conditions these people have? *

  1. Burkitt Lymphoma (cancer of the lymphatic system): 8 people, 17.39%
  2. Type 2 Diabetes: 6 people, 13.04%
  3. Multiple Myeloma (cancer of the plasma cells): 5 people, 10.87%
  4. High Blood Pressure: 5 people, 10.87%
  5. Hiv Infection: 5 people, 10.87%
  6. Pain: 5 people, 10.87%
  7. Cytomegalovirus Infection: 4 people, 8.70%
  8. Urination - Excessive Volume: 4 people, 8.70%
  9. Productive Cough: 4 people, 8.70%
  10. Nausea (feeling of having an urge to vomit): 3 people, 6.52%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Metformin and Ganciclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ganciclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metformin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ganciclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride and ganciclovir (the active ingredients of Metformin and Ganciclovir, respectively), and Metformin and Ganciclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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