Metformin and Hyrimoz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Hyrimoz (adalimumab-adaz). Common drug interactions include red blood cell count decreased among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Hyrimoz. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,355 Metformin users. Check the latest studies of Metformin.

What is Hyrimoz?

Hyrimoz has active ingredients of adalimumab-adaz. eHealthMe is studying from 4,635 Hyrimoz users. Check the latest studies of Hyrimoz.

On Aug, 09, 2026

67 people who take Metformin and Hyrimoz together, and have interactions are studied.

Metformin and Hyrimoz drug interactions.

What are the common drug interactions of Metformin and Hyrimoz, by gender? *:

female:

Red blood cell count decreased
Abscess (pus)
Cellulitis (infection under the skin)
Depressive symptom
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)
Pain
Colitis ulcerative (inflammation of colon with ulcer)
Diabetic foot
Foot deformity (functional disability of foot)
Impaired healing

male:

Pain
Arthralgia (joint pain)
Neck pain
Haematochezia (passage of stools containing blood)
Pneumonia
Psoriasis (immune-mediated disease that affects the skin)
Back pain
Joint swelling
Abdominal pain upper
Alanine aminotransferase increased

What are the common drug interactions of Metformin and Hyrimoz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Abscess (pus)
Cellulitis (infection under the skin)
Depressive symptom
Idiopathic intracranial hypertension (elevated cerebrospinal fluid pressure of unknown cause)
Pain
Colitis ulcerative (inflammation of colon with ulcer)
Nausea (feeling of having an urge to vomit)

30-39:

Abdominal discomfort
Drug ineffective
Quality of life decreased

40-49:

Abdominal pain
Abdominal pain upper
Arthralgia (joint pain)
Back pain
Colitis (inflammation of colon)
Colitis ulcerative (inflammation of colon with ulcer)
Drug intolerance (drug sensitivity)
Gastrointestinal pain
Headache (pain in head)
Pain in extremity

50-59:

Pruritus (severe itching of the skin)
Normochromic normocytic anaemia (forms of anaemia in which the average size and haemoglobin content of the red blood cells are within normal limits)
Pneumonia
Pulmonary sepsis (pus in lungs)
Arthralgia (joint pain)
Disease recurrence
Gait disturbance
Grip strength decreased
Groin abscess (pus in groin)
Hidradenitis (chronic disease of a type of sweat gland)

60+:

Arthralgia (joint pain)
Abdominal pain
Abdominal pain lower
Ageusia (loss of taste functions of the tongue)
Aphthous ulcer (mouth ulcer)
Atrioventricular block (heart block)
Back pain
Eye pain
Fistula (an abnormal connection or passageway between two)
Ileal stenosis (obstruction in the ileal)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 25.37%
Psoriasis (immune-mediated disease that affects the skin): 17 people, 25.37%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 12 people, 17.91%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 10 people, 14.93%
Hidradenitis (chronic disease of a type of sweat gland): 8 people, 11.94%
High Blood Pressure: 7 people, 10.45%
Pain: 4 people, 5.97%
Nodule (a growth of abnormal tissue): 4 people, 5.97%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 5.97%
Abscess (pus): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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