Metformin and Tracrium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Tracrium (atracurium besylate). Common drug interactions include toxic skin eruption among females and anaphylactic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Metformin and Tracrium. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,358 Metformin users. Check the latest studies of Metformin.

What is Tracrium?

Tracrium has active ingredients of atracurium besylate. eHealthMe is studying from 909 Tracrium users. Check the latest studies of Tracrium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

28 people who take Metformin and Tracrium together, and have interactions are studied.

Metformin and Tracrium drug interactions.

What are the common drug interactions of Metformin and Tracrium, by gender? *:

female:

Toxic skin eruption (skin breakdown due to toxic substance)
Anuria (failure of the kidneys to produce urine)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)
Acute respiratory distress syndrome
Bacteroides infection (infection of bacteroides-a genus of gram-negative, bacillus bacteria)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Asthma
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

male:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Generalised erythema (redness of the skin all over the body)
Hypotension (abnormally low blood pressure)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaphylactic reaction (serious allergic reaction)
Cardiac arrest
Renal failure acute (rapid kidney dysfunction)

What are the common drug interactions of Metformin and Tracrium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Pleural effusion (water on the lungs)
Septic shock (shock due to blood infection)
Toxic skin eruption (skin breakdown due to toxic substance)
Anuria (failure of the kidneys to produce urine)
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Renal failure (kidney dysfunction)
Respiratory distress (difficulty in breathing)
Acute respiratory distress syndrome
Bacteroides infection (infection of bacteroides-a genus of gram-negative, bacillus bacteria)

50-59:

Hypotension (abnormally low blood pressure)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Generalised erythema (redness of the skin all over the body)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Renal failure acute (rapid kidney dysfunction)

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Anaphylactic reaction (serious allergic reaction)
Cardiac arrest

What are the existing conditions these people have? *

Type 2 Diabetes: 5 people, 17.86%
General Anaesthesia: 3 people, 10.71%
Enterobacter Infection (infection caused by bacteria of the family enterobacteriaceae): 2 people, 7.14%
Bacteroides Infection (infection of bacteroides-a genus of gram-negative, bacillus bacteria): 2 people, 7.14%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 7.14%
Anaesthesia: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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