Metformin and Vermox drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Metformin (metformin hydrochloride) and Vermox (mebendazole). Common drug interactions include chronic kidney disease among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Metformin and Vermox. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Metformin?
Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.
What is Vermox?
Vermox has active ingredients of mebendazole. It is often used in pinworms. eHealthMe is studying from 572 Vermox users. Check the latest studies of Vermox.
16 people who take Metformin and Vermox together, and have interactions are studied.

What are the common drug interactions of Metformin and Vermox, by gender? *:
female:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Haematocrit decreased
- Haemoglobin decreased
- Lymphocyte count decreased
- Macrocytosis (enlargement of red blood cells with near-constant haemoglobin concentration)
- Metrorrhagia (uterine bleeding at irregular intervals)
- Nausea (feeling of having an urge to vomit)
- Neoplasm progression (growth of tumour)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
male:
- Depression
- Fear of disease
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Dry eye (lack of adequate tears)
- Dry mouth
- Dry skin
- Ejaculation failure
- Fatigue (feeling of tiredness)
- Hypohidrosis (lack of sweating)
- Illusion
What are the common drug interactions of Metformin and Vermox, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abnormal dreams
- Chapped lips (cracking, fissuring, and peeling of the skin f lip)
- Dry eye (lack of adequate tears)
- Dry mouth
- Dry skin
- Ejaculation failure
- Fatigue (feeling of tiredness)
- Hypohidrosis (lack of sweating)
- Illusion
- Insomnia (sleeplessness)
50-59:
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
60+:
- Haematocrit decreased
- Haemoglobin decreased
- Red cell distribution width increased
- Reticulocytosis (a condition where there is an increase in reticulocytes)
- White blood cell count decreased
- Blood disorder
- Bone marrow disorder
- Full blood count decreased
- Mean cell volume increased (more than normal average red blood cell volume)
- Reflux gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile)
What are the existing conditions these people have? *
- Pain: 11 people, 68.75%
- Blood Pressure Abnormal: 11 people, 68.75%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 9 people, 56.25%
- High Blood Pressure: 6 people, 37.50%
- Dyspnea (difficult or laboured breathing): 3 people, 18.75%
- Constipation: 3 people, 18.75%
- Depression: 3 people, 18.75%
- Sleep Disorder: 2 people, 12.50%
- Breast Cancer Metastatic: 2 people, 12.50%
- Chest Injury: 2 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Metformin and Vermox?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Metformin and Vermox:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Metformin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vermox:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Metformin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vermox and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride and mebendazole (the active ingredients of Metformin and Vermox, respectively), and Metformin and Vermox (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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