Zerit and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Zerit (stavudine) and Metformin (metformin hydrochloride). Common drug interactions include asocial behaviour among females and emotional distress among males.

The phase IV clinical study analyzes what interactions people have when they take Zerit and Metformin. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Zerit?

Zerit has active ingredients of stavudine. eHealthMe is studying from 9,912 Zerit users. Check the latest studies of Zerit.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.

On Jul, 14, 2026

53 people who take Zerit and Metformin together, and have interactions are studied.

What are the common drug interactions of Zerit and Metformin, by gender? *:

female:

Asocial behaviour
Blood cholesterol increased
Blood creatinine increased
Bone density decreased
Bone pain
Depressed mood
Dizziness
Dysstasia (difficulty in standing)
Fatigue (feeling of tiredness)
Foot fracture

male:

Emotional distress
Pain
Nephrolithiasis (calculi in the kidneys)
Depression
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Gait disturbance
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Impaired work ability
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

What are the common drug interactions of Zerit and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anal cancer stage 0
B-cell lymphoma (blood cancer affecting b cells)
Blood cholesterol increased
Bone neoplasm malignant (cancer of bone)
Colon cancer
Drug ineffective
Nausea (feeling of having an urge to vomit)
Neoplasm malignant (cancer tumour)
Neuropathy peripheral (surface nerve damage)
Obesity (having too much body fat)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Renal impairment (severely reduced kidney function)
Renal failure (kidney dysfunction)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Decreased activity
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)

50-59:

Fear
Fracture
Glomerular filtration rate decreased
Glomerulonephritis membranous (nephritis with inflammation of the capillary loops in the renal glomeruli)
Hand fracture
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Joint range of motion decreased (disease of joint movement)
Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
Nausea (feeling of having an urge to vomit)

60+:

Emotional distress
Pain
Depression
Gait disturbance
Lactic acidosis (low ph in body tissues)
Post-traumatic stress disorder
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Blood lactate dehydrogenase increased
Blood ph decreased
Blood pressure systolic decreased

What are the existing conditions these people have? *

Hiv Infection: 45 people, 84.91%
High Blood Pressure: 15 people, 28.30%
High Blood Cholesterol: 13 people, 24.53%
Depression: 10 people, 18.87%
Pain: 7 people, 13.21%
Neuralgia (pain in one or more nerves): 7 people, 13.21%
Urinary Retention (the inability to completely or partially empty the bladder): 6 people, 11.32%
Erection Problems: 6 people, 11.32%
Cardiac Disorder: 5 people, 9.43%
Insomnia (sleeplessness): 4 people, 7.55%

* Approximation only. Some reports may have incomplete information.

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