Methimazole and Ativan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methimazole (methimazole) and Ativan (lorazepam). Common drug interactions include cough among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Methimazole and Ativan. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

What is Ativan?

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 78,506 Ativan users. Check the latest studies of Ativan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

82 people who take Methimazole and Ativan together, and have interactions are studied.

Methimazole and Ativan drug interactions.

What are the common drug interactions of Methimazole and Ativan, by gender? *:

female:

Cough
Decreased appetite
Haemarthrosis (haemarthrosis is where blood is able to enter the joint capsule)
Iron deficiency anaemia
Occult blood positive
Oral pain
Apical granuloma (tumour of the apex of a nonvital tooth)
Ear pain
Gingival swelling (gums swelling)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)

male:

Fatigue (feeling of tiredness)
Anaemia (lack of blood)
Asthenia (weakness)
Back pain
Blood creatinine increased
Blood culture positive
Blood pressure decreased
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Confusional state
Culture urine positive

What are the common drug interactions of Methimazole and Ativan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Hypersensitivity
Poor venous access
Colitis (inflammation of colon)
Impaired gastric emptying
Oesophagitis (inflammation of oesophagus)
Contusion (a type of hematoma of tissue in which capillaries)
Irritable bowel syndrome
Abdominal distension
Agitation (state of anxiety or nervous excitement)
Asthenia (weakness)

30-39:

Nephrogenic fibrosing dermopathy (involves fibrosis of skin, joints, eyes due to kidney disease)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiogenic shock (inadequate circulation of blood)
Death
Septic shock (shock due to blood infection)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Blood pressure increased
Heart rate increased
Injection site pain

40-49:

Fatigue (feeling of tiredness)
Anaemia (lack of blood)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Malaise (a feeling of general discomfort or uneasiness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Weight increased
Actinomycosis (infection that causes sores, or abscesses)
Alopecia (absence of hair from areas of the body)
Atelectasis (partial or complete collapse of the lung)
Bone disorder

50-59:

Gastritis (inflammation of stomach)
Hypertension (high blood pressure)
Rectal haemorrhage (bleeding from anus)
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Alopecia (absence of hair from areas of the body)
Blood creatine phosphokinase increased
Blood pressure decreased
Fall
Hair colour changes
Hair disorder

60+:

Fatigue (feeling of tiredness)
Decreased appetite
Dyspepsia (indigestion)
Fall
Headache (pain in head)
Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Pneumonia
Renal failure (kidney dysfunction)
Retinal haemorrhage (bleeding from retina)

What are the existing conditions these people have? *

Breast Cancer: 14 people, 17.07%
Pain: 13 people, 15.85%
Metastases To Bone (cancer spreads to bone): 11 people, 13.41%
Chronic Thyroiditis (long lasting inflammation of thyroid gland): 11 people, 13.41%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 10 people, 12.20%
Multiple Myeloma (cancer of the plasma cells): 10 people, 12.20%
Birth Control: 9 people, 10.98%
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones): 9 people, 10.98%
Insomnia (sleeplessness): 6 people, 7.32%
Nausea (feeling of having an urge to vomit): 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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