Methimazole and Pregabalin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methimazole (methimazole) and Pregabalin (pregabalin). Common drug interactions include axonal neuropathy among females and back injury among males.
The phase IV clinical study analyzes what interactions people have when they take Methimazole and Pregabalin. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.
What is Methimazole?
Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.
What is Pregabalin?
Pregabalin has active ingredients of pregabalin. It is often used in fibromyalgia. eHealthMe is studying from 74,069 Pregabalin users. Check the latest studies of Pregabalin.
34 people who take Methimazole and Pregabalin together, and have interactions are studied.

What are the common drug interactions of Methimazole and Pregabalin, by gender? *:
female:
- Axonal neuropathy (dysfunction of axon nerves)
- Ankle fracture
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Blood glucose increased
- Chest discomfort
- Conjunctivitis (pink eye)
- Cystitis (inflammation of the wall of the bladder)
- Dehydration (dryness resulting from the removal of water)
male:
- Back injury
- Bacteraemia (presence of bacteria in the blood)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Fall
- Glycosylated haemoglobin increased
- Hyperaesthesia
- Influenza like illness
- International normalised ratio increased
- Lower respiratory tract infection bacterial
What are the common drug interactions of Methimazole and Pregabalin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Chest pain
- Diarrhoea
- Dizziness
- Influenza
- Nausea (feeling of having an urge to vomit)
- Vertigo
- Vision blurred
30-39:
n/a
40-49:
- Hyperaesthesia
50-59:
- Blood glucose increased
- Alopecia (absence of hair from areas of the body)
- Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
- Chest discomfort
- Conjunctivitis (pink eye)
- Dehydration (dryness resulting from the removal of water)
- Dizziness
- Dyspnoea (difficult or laboured respiration)
- Endocrine ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism)
- Fall
60+:
- Axonal neuropathy (dysfunction of axon nerves)
- Urinary tract infection
- Dehydration (dryness resulting from the removal of water)
- Dysuria (painful or difficult urination)
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Fatigue (feeling of tiredness)
- Gastroenteritis (inflammation of stomach and intestine)
- Hemiparesis (weakness on one side of the body)
- Influenza like illness
- International normalised ratio increased
What are the existing conditions these people have? *
- High Blood Pressure: 10 people, 29.41%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 20.59%
- Axonal Neuropathy (dysfunction of axon nerves): 5 people, 14.71%
- Dyslipidaemia (abnormal amount of lipids): 5 people, 14.71%
- Pain: 5 people, 14.71%
- Osteoporosis (bones weak and more likely to break): 5 people, 14.71%
- Abdominal Pain: 4 people, 11.76%
- Lung Cancer - Non-Small Cell (lung cancer): 4 people, 11.76%
- Tumor Pain: 4 people, 11.76%
- Multiple Myeloma (cancer of the plasma cells): 4 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Methimazole and Pregabalin?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methimazole (8,016 reports)
- Pregabalin (74,069 reports)
Browse all drug interactions of Methimazole and Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methimazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Pregabalin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methimazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Pregabalin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
- de Landaluce, L. O., Carbonell, P., Asensio, C., Escoda, N., López, P., & Laporte, J. R. , "Gabapentin and Pregabalin and Risk of Atrial Fibrillation in the Elderly: A Population-Based Cohort Study in an Electronic Prescription Database", Drug safety, 2018 Jan .
- Bonnet U, Taazimi B, Grabbe HD, "Pregabalin-Related Hypertriglyceridemia", Psychosomatics, 2014 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on methimazole and pregabalin (the active ingredients of Methimazole and Pregabalin, respectively), and Methimazole and Pregabalin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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