Methimazole and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methimazole (methimazole) and Tracleer (bosentan). Common drug interactions include fall among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Methimazole and Tracleer. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Methimazole?

Methimazole has active ingredients of methimazole. It is often used in hyperthyroidism. eHealthMe is studying from 8,016 Methimazole users. Check the latest studies of Methimazole.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.

On Jul, 26, 2026

19 people who take Methimazole and Tracleer together, and have interactions are studied.

Methimazole and Tracleer drug interactions.

What are the common drug interactions of Methimazole and Tracleer, by gender? *:

female:

Fall
Abdominal pain upper
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Atrioventricular block (heart block)
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

male:

Abdominal distension
Arthralgia (joint pain)
International normalised ratio increased
Oedema peripheral (superficial swelling)
Pain
Right ventricular failure (right half of the heart fails to work)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Activities of daily living impaired
Death

What are the common drug interactions of Methimazole and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Dental care

10-19:

Eye disorder

20-29:

Abdominal pain upper
Atrioventricular block (heart block)
Pneumonia
Seizure like phenomena (a variety of medical conditions may produce sudden episodes which have some similarities to epileptic seizures)
Syncope (loss of consciousness with an inability to maintain postural tone)

30-39:

n/a

40-49:

Death

50-59:

Generalised oedema (swelling all over the body)
Oedema peripheral (superficial swelling)
Weight increased
Abdominal distension
Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Cardiac failure acute
Cardiac failure high output
Dyspnoea (difficult or laboured respiration)
Fluid retention (an abnormal accumulation of fluid in the blood)
Pleural effusion (water on the lungs)

60+:

Fall
Arthralgia (joint pain)
Activities of daily living impaired
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure acute
Cardiac failure high output
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)

What are the existing conditions these people have? *

Wheezing (a high-pitched whistling sound made while you breath): 2 people, 10.53%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 10.53%
Dyspnea (difficult or laboured breathing): 2 people, 10.53%
Abdominal Pain: 2 people, 10.53%
High Blood Pressure: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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