Methylcobalamin and Mesalamine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylcobalamin (vitamin b12) and Mesalamine (mesalamine). Common drug interactions include arthralgia among females and pneumonia bacterial among males.

The phase IV clinical study analyzes what interactions people have when they take Methylcobalamin and Mesalamine. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Methylcobalamin?

Methylcobalamin has active ingredients of vitamin b12. It is often used in vitamin b12 deficiency. eHealthMe is studying from 3,184 Methylcobalamin users. Check the latest studies of Methylcobalamin.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 28,053 Mesalamine users. Check the latest studies of Mesalamine.

On Jul, 14, 2026

27 people who take Methylcobalamin and Mesalamine together, and have interactions are studied.

Methylcobalamin and Mesalamine drug interactions.

What are the common drug interactions of Methylcobalamin and Mesalamine, by gender? *:

female:

Arthralgia (joint pain)
Fatigue (feeling of tiredness)
Muscular weakness (muscle weakness)
Anxiety
Blood pressure decreased
Constipation
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Diarrhoea
Haematochezia (passage of stools containing blood)
Haemoglobin decreased

male:

Pneumonia bacterial (pneumonia associated with bacterial infection)
Pneumonia
Loss of consciousness
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Nightmare (unpleasant dream)
Pleural effusion (water on the lungs)
Rales (an abnormal respiratory sound characterized by fine crackles)
Sepsis (a severe blood infection that can lead to organ failure and death)
Sleep paralysis (waking up and unable to move or speak)
Superinfection

What are the common drug interactions of Methylcobalamin and Mesalamine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Pneumonia
Pneumonia bacterial (pneumonia associated with bacterial infection)

30-39:

Anxiety
Heart rate decreased
Hypotension (abnormally low blood pressure)
Palpitations (feelings or sensations that your heart is pounding or racing)
Precancerous skin lesion
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Surgery

40-49:

Abdominal abscess (collection of pus in abdomen)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Nausea (feeling of having an urge to vomit)
Vomiting

50-59:

Cold sweat
Dyspnoea (difficult or laboured respiration)
Hypoaesthesia (reduced sense of touch or sensation)
Loss of consciousness
Nightmare (unpleasant dream)
Sleep paralysis (waking up and unable to move or speak)
Tremor (trembling or shaking movements in one or more parts of your body)

60+:

Arthralgia (joint pain)
Muscular weakness (muscle weakness)
Asthenia (weakness)
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Grip strength decreased
Mobility decreased (ability to move is reduced)
Skin infection
Skin wound

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 33.33%
Abdominal Discomfort: 6 people, 22.22%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 14.81%
Inflammatory Bowel Disease: 2 people, 7.41%
Depression: 2 people, 7.41%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Methylcobalamin and Mesalamine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously