Methylcobalamin and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylcobalamin (vitamin b12) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include swelling face among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Methylcobalamin and Valacyclovir. It is created by eHealthMe based on reports of 56 people who take the same drugs from the FDA, and is updated regularly.

What is Methylcobalamin?

Methylcobalamin has active ingredients of vitamin b12. It is often used in vitamin b12 deficiency. eHealthMe is studying from 3,184 Methylcobalamin users. Check the latest studies of Methylcobalamin.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,107 Valacyclovir users. Check the latest studies of Valacyclovir.

On Jul, 27, 2026

56 people who take Methylcobalamin and Valacyclovir together, and have interactions are studied.

Methylcobalamin and Valacyclovir drug interactions.

What are the common drug interactions of Methylcobalamin and Valacyclovir, by gender? *:

female:

Swelling face
Tooth extraction
Upper limb fracture
Urticaria (rash of round, red welts on the skin that itch intensely)
Vitiligo (pigment is lost from areas of the skin)
Diarrhoea
Hyperhidrosis (abnormally increased sweating)
Pyrexia (fever)
Dizziness
Drug hypersensitivity

male:

Pneumonia
Tuberculous pleurisy (an inflammation of lung covering plura by mycobacterium tuberculosis)
Pain in extremity
Peripheral coldness
Platelet count decreased
Anaemia (lack of blood)
Cytomegalovirus infection
Death
Decreased appetite
Gastrointestinal infection (infection of stomach and intestine)

What are the common drug interactions of Methylcobalamin and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cytomegalovirus infection
Gastrointestinal infection (infection of stomach and intestine)
Large intestinal ulcer
Allergy to animal
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Conjunctival hyperaemia (congestion of conjunctival vessels)
Eye pruritus (eye itching)
Facial paralysis (loss of function of face muscle)
Haematochezia (passage of stools containing blood)
Intraocular pressure increased

40-49:

Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood pressure decreased
Heart rate increased
Oxygen saturation decreased
Peripheral coldness
Drug hypersensitivity
Abdominal discomfort
Abdominal pain

50-59:

Abdominal pain
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Platelet count decreased
Regurgitation (expulsion of material)
Abdominal pain upper
Anaemia (lack of blood)
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Death
Diarrhoea

60+:

Pneumonia
Tuberculous pleurisy (an inflammation of lung covering plura by mycobacterium tuberculosis)
Insomnia (sleeplessness)
Pain in extremity
Pyrexia (fever)
Constipation
Drug hypersensitivity
Hypoxia (low oxygen in tissues)
Intestinal obstruction
Renal impairment (severely reduced kidney function)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 21 people, 37.50%
High Blood Pressure: 11 people, 19.64%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 8 people, 14.29%
Herpes Zoster: 7 people, 12.50%
Productive Cough: 7 people, 12.50%
Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 12.50%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 6 people, 10.71%
Diarrhea: 6 people, 10.71%
Cough: 6 people, 10.71%
Blood Uric Acid Increased: 6 people, 10.71%

* Approximation only. Some reports may have incomplete information.

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