Methyldopa and Celebrex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methyldopa (methyldopa) and Celebrex (celecoxib). Common drug interactions include dyspnoea among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Methyldopa and Celebrex. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Methyldopa?

Methyldopa has active ingredients of methyldopa. It is often used in high blood pressure. eHealthMe is studying from 6,475 Methyldopa users. Check the latest studies of Methyldopa.

What is Celebrex?

Celebrex has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 151,106 Celebrex users. Check the latest studies of Celebrex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

44 people who take Methyldopa and Celebrex together, and have interactions are studied.

Methyldopa and Celebrex drug interactions.

What are the common drug interactions of Methyldopa and Celebrex, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Injury
Tardive dyskinesia (a disorder that involves involuntary movements)
Visual impairment
Arthralgia (joint pain)
Chest pain
Constipation

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

What are the common drug interactions of Methyldopa and Celebrex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abortion spontaneous (naturally occurring miscarriage)
Cough
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Pneumonia
Pyrexia (fever)
Rash papular (redness with papule)
Rash pruritic (redness with itching)

40-49:

Abortion spontaneous (naturally occurring miscarriage)
Maternal exposure during pregnancy (use of substance during pregnancy)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Chest pain
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
Abdominal distension
Abdominal pain
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)

50-59:

Arthralgia (joint pain)
Asthma
Back pain
Bile duct stone
Blood chloride decreased
Blood glucose decreased
Blood glucose increased
Blood immunoglobulin g increased
Blood sodium decreased
Blood thyroid stimulating hormone decreased

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Visual impairment
Alopecia (absence of hair from areas of the body)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Cough
Drug effect decreased
Embolic stroke (stroke due to obstruction due to an embolus)
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Hallucination (an experience involving the perception of something not present)

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 13.64%
Pain: 6 people, 13.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 11.36%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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