Methylfolate and Pantoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylfolate (folic acid) and Pantoprazole (pantoprazole sodium). Common drug interactions include pain among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Methylfolate and Pantoprazole. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Methylfolate?

Methylfolate has active ingredients of folic acid. eHealthMe is studying from 1,018 Methylfolate users. Check the latest studies of Methylfolate.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.

On Jul, 09, 2026

47 people who take Methylfolate and Pantoprazole together, and have interactions are studied.

Methylfolate and Pantoprazole drug interactions.

What are the common drug interactions of Methylfolate and Pantoprazole, by gender? *:

female:

Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Anxiety
Gait disturbance
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Foot fracture
Oropharyngeal pain
Accident at home
Asthenia (weakness)
Blood pressure increased

male:

Loss of consciousness
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Tooth infection
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Heart rate increased

What are the common drug interactions of Methylfolate and Pantoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest pain
Electrocardiogram qt prolonged
Nausea (feeling of having an urge to vomit)
Syncope (loss of consciousness with an inability to maintain postural tone)
Vomiting

30-39:

Eye disorder
Fatigue (feeling of tiredness)
Flushing (the warm, red condition of human skin)
Heart rate increased
Nausea (feeling of having an urge to vomit)
Neuralgia (pain in one or more nerves)
Optic neuritis (optic nerve inflammation)
Pain
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Sensation of foreign body

40-49:

Feeling hot
Heart rate increased
Oral mucosal blistering (mouth ulcer)
Stomatitis (inflammation of mucous membrane of mouth)

50-59:

Gait disturbance
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)
Pain
Tremor (trembling or shaking movements in one or more parts of your body)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Fall

60+:

Fatigue (feeling of tiredness)
Oropharyngeal pain
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Confusional state
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Hyperhidrosis (abnormally increased sweating)
Insomnia (sleeplessness)

What are the existing conditions these people have? *

Pain: 8 people, 17.02%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 17.02%
Sleep Disorder: 7 people, 14.89%
Nausea (feeling of having an urge to vomit): 7 people, 14.89%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 14.89%
Constipation: 7 people, 14.89%
Hypersensitivity: 6 people, 12.77%
Cardiac Disorder: 6 people, 12.77%
High Blood Cholesterol: 6 people, 12.77%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 10.64%

* Approximation only. Some reports may have incomplete information.

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