Methylphenidate hydrochloride and Lipitor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate hydrochloride (methylphenidate hydrochloride) and Lipitor (atorvastatin calcium). Common drug interactions include chronic kidney disease among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate hydrochloride and Lipitor. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate hydrochloride?

Methylphenidate hydrochloride has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 6,822 Methylphenidate hydrochloride users. Check the latest studies of Methylphenidate hydrochloride.

What is Lipitor?

Lipitor has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. eHealthMe is studying from 259,047 Lipitor users. Check the latest studies of Lipitor.

On Jul, 15, 2026

57 people who take Methylphenidate hydrochloride and Lipitor together, and have interactions are studied.

Methylphenidate hydrochloride and Lipitor drug interactions.

What are the common drug interactions of Methylphenidate Hydrochloride and Lipitor, by gender? *:

female:

Chronic kidney disease
Confusional state
Death
Decreased appetite
Dizziness
Faeces discoloured
Head injury
Infusion site bruising
Infusion site pain
Nausea (feeling of having an urge to vomit)

male:

Hallucination (an experience involving the perception of something not present)
Drug ineffective
Agitation (state of anxiety or nervous excitement)
Dyspnoea (difficult or laboured respiration)
Insomnia (sleeplessness)
Oedema peripheral (superficial swelling)
Tremor (trembling or shaking movements in one or more parts of your body)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cellulitis (infection under the skin)
Chronic kidney disease

What are the common drug interactions of Methylphenidate Hydrochloride and Lipitor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Anger
Bruxism (habitual grinding of the teeth, typically during sleep)
Emotional disorder

40-49:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Personality change
Pneumonia
Productive cough
Rales (an abnormal respiratory sound characterized by fine crackles)
Rash
Respiratory disorder (respiratory disease)
Respiratory rate increased (excess breathing rate/min)
Respiratory tract infection

50-59:

Agitation (state of anxiety or nervous excitement)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Diarrhoea
Facial palsy (paralysis of face nerve)
Flushing (the warm, red condition of human skin)
Hemiparesis (weakness on one side of the body)
Hyperhidrosis (abnormally increased sweating)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Insomnia (sleeplessness)

60+:

Drug ineffective
Pneumonia
Weight decreased
Abdominal pain upper
Death
Dry mouth
Faeces discoloured
Nephrogenic anaemia (anaemia due to kidney disease)
Oropharyngeal pain
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 17.54%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 14.04%
Psychotic Disorder: 7 people, 12.28%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 7 people, 12.28%
High Blood Pressure: 7 people, 12.28%
Depression: 7 people, 12.28%
Hallucinations (sensations that appear real but are created by your mind): 6 people, 10.53%
Nicotine Dependence: 5 people, 8.77%
Pain: 4 people, 7.02%
Hepatocellular Carcinoma (liver cancer): 4 people, 7.02%

* Approximation only. Some reports may have incomplete information.

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