Methylphenidate and Adenosine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate (methylphenidate) and Adenosine (adenosine). Common drug interactions include cataract among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate and Adenosine. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Adenosine?

Adenosine has active ingredients of adenosine. eHealthMe is studying from 2,711 Adenosine users. Check the latest studies of Adenosine.



On Jul, 14, 2026

16 people who take Methylphenidate and Adenosine together, and have interactions are studied.

Methylphenidate and Adenosine drug interactions.

What are the common drug interactions of Methylphenidate and Adenosine, by gender? *:

female:

  1. Cataract (clouding of the lens inside the eye)
  2. Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
  3. Neuropathy peripheral (surface nerve damage)
  4. Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
  5. Chronic kidney disease
  6. Blood pressure increased
  7. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  8. Acute myocardial infarction (acute heart attack)
  9. Anxiety
  10. Liver injury

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Decreased activity
  4. Emotional distress
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Osteoporosis (bones weak and more likely to break)
  7. Pain
  8. Quality of life decreased
  9. Upper limb fracture
  10. Spinal compression fracture (fracture due to spinal compression on bone)

What are the common drug interactions of Methylphenidate and Adenosine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Decreased activity
  4. Emotional distress
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Osteoporosis (bones weak and more likely to break)
  7. Pain
  8. Quality of life decreased
  9. Spinal compression fracture (fracture due to spinal compression on bone)
  10. Upper limb fracture

50-59:

  1. Acute myocardial infarction (acute heart attack)

60+:

  1. Cataract (clouding of the lens inside the eye)
  2. Myofascial pain syndrome (a painful condition that affects the muscles and the sheath of the tissue)
  3. Neuropathy peripheral (surface nerve damage)
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Stress urinary incontinence (leak urine with things like coughing, sneezing or exercise)
  6. Back pain
  7. Blood pressure increased
  8. Chronic kidney disease
  9. Liver injury
  10. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 62.50%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 37.50%
  3. Hiv Infection: 3 people, 18.75%
  4. Drowsiness: 3 people, 18.75%
  5. Apnea (temporary absence or cessation of breathing): 3 people, 18.75%
  6. Renal Cell Carcinoma (a kidney cancer): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Methylphenidate and Adenosine?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Methylphenidate and Adenosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adenosine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylphenidate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adenosine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate and adenosine (the active ingredients of Methylphenidate and Adenosine, respectively), and Methylphenidate and Adenosine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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