Methylphenidate and Claritin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate (methylphenidate) and Claritin (loratadine). Common drug interactions include feeling drunk among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate and Claritin. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,217 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,317 Claritin users. Check the latest studies of Claritin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

90 people who take Methylphenidate and Claritin together, and have interactions are studied.

Methylphenidate and Claritin drug interactions.

What are the common drug interactions of Methylphenidate and Claritin, by gender? *:

female:

Feeling drunk
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Heart rate increased
Hysterectomy
Influenza
Insomnia (sleeplessness)
Lower limb fracture
Muscle spasms (muscle contraction)
Nasopharyngitis (inflammation of the nasopharynx)
Nephrolithiasis (calculi in the kidneys)

male:

Anxiety
Nasopharyngitis (inflammation of the nasopharynx)
Limb injury
Lyme disease (a bacterial infection that is spread to humans by infected ticks)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Sleep disorder
Suicidal ideation
Therapeutic response unexpected
Tremor (trembling or shaking movements in one or more parts of your body)

What are the common drug interactions of Methylphenidate and Claritin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Irritability
Oral herpes (viral infection of mouth)
Aggression
Anger
Anxiety
Asthma
Blood lactic acid increased
Daydreaming
Disturbance in attention
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)

20-29:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Sinus congestion (blockage of sinus)
Tinnitus (a ringing in the ears)
Urticaria (rash of round, red welts on the skin that itch intensely)
Vomiting
Weight decreased
Nausea (feeling of having an urge to vomit)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood pressure diastolic increased

30-39:

Blood pressure increased
Confusional state
Depression
Feeling drunk
Headache (pain in head)
Adrenal disorder
Adverse reaction
Anaphylactic reaction (serious allergic reaction)
Bipolar disorder (mood disorder)
Chills (felling of cold)

40-49:

Chronic kidney disease
Nasopharyngitis (inflammation of the nasopharynx)
Ankle fracture
Anxiety
Blood cholesterol increased
Cough
Essential hypertension (primary hypertension)
Fall
Hypotension (abnormally low blood pressure)
Nocturia (the need to get up in the night to urinate)

50-59:

Fall
Fatigue (feeling of tiredness)
Full blood count decreased
Insomnia (sleeplessness)
Nasopharyngitis (inflammation of the nasopharynx)
Nightmare (unpleasant dream)
Oxygen saturation decreased
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Therapeutic response unexpected
Urinary tract infection

60+:

Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Fall
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 57 people, 63.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 34 people, 37.78%
Drowsiness: 11 people, 12.22%
Asthma: 5 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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