Methylphenidate and Marinol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylphenidate (methylphenidate) and Marinol (dronabinol). Common drug interactions include vomiting among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Methylphenidate and Marinol. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

What is Marinol?

Marinol has active ingredients of dronabinol. It is often used in pain. eHealthMe is studying from 4,963 Marinol users. Check the latest studies of Marinol.

On Jul, 05, 2026

17 people who take Methylphenidate and Marinol together, and have interactions are studied.

Methylphenidate and Marinol drug interactions.

What are the common drug interactions of Methylphenidate and Marinol, by gender? *:

female:

Vomiting
Failure to thrive (inadequate weight gain and physical growth in children)
Fatigue (feeling of tiredness)
Asthenia (weakness)
Decreased appetite
Eye allergy
Abdominal pain
Adverse drug reaction
Anaemia (lack of blood)
Back pain

male:

Acute respiratory failure
Cerebral haemorrhage (bleeding within the brain)
Sepsis (a severe blood infection that can lead to organ failure and death)
Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
Pancreatic pseudocyst (collection of tissue and fluids that forms on pancreas)
Chronic kidney disease
Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Blood creatinine increased

What are the common drug interactions of Methylphenidate and Marinol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Vomiting
Asthenia (weakness)
Decreased appetite
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Eating disorder
Failure to thrive (inadequate weight gain and physical growth in children)
Fatigue (feeling of tiredness)
Gait disturbance
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)

50-59:

Acute respiratory failure
Cerebral haemorrhage (bleeding within the brain)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Fall
Ileus (a painful obstruction of the ileum or other part of the intestine)
Loss of consciousness
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pancreatitis acute (sudden inflammation of pancreas)
Pancreatitis necrotising (inflammation of the pancreas cause death of tissue in pancreas)
Pneumonia

60+:

Anaemia (lack of blood)
Blood creatinine increased
Renal failure (kidney dysfunction)
Abdominal pain
Adverse drug reaction
Back pain
Constipation
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Type 2 Diabetes: 4 people, 23.53%
Nausea (feeling of having an urge to vomit): 4 people, 23.53%
Diarrhea: 4 people, 23.53%
Nausea And Vomiting: 4 people, 23.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 17.65%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 11.76%
Immunodeficiency Common Variable: 2 people, 11.76%
Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 11.76%
Hiv Infection: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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