Methylprednisolone and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Methylprednisolone (methylprednisolone) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include arthralgia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Methylprednisolone and Centrum. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Methylprednisolone?

Methylprednisolone has active ingredients of methylprednisolone. It is often used in inflammation. eHealthMe is studying from 59,645 Methylprednisolone users. Check the latest studies of Methylprednisolone.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.

On Jul, 10, 2026

41 people who take Methylprednisolone and Centrum together, and have interactions are studied.

Methylprednisolone and Centrum drug interactions.

What are the common drug interactions of Methylprednisolone and Centrum, by gender? *:

female:

Arthralgia (joint pain)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pain
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Abdominal pain upper
Anxiety
Back pain
Chest discomfort

male:

Pain
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Emotional disorder
Malaise (a feeling of general discomfort or uneasiness)
Injury
Multiple injuries
Syncope (loss of consciousness with an inability to maintain postural tone)
Blood pressure immeasurable

What are the common drug interactions of Methylprednisolone and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Arthralgia (joint pain)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injury
Oedema peripheral (superficial swelling)
Pain

30-39:

Alanine aminotransferase increased
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Aspartate aminotransferase increased
Blood bilirubin increased
Chills (felling of cold)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Colitis (inflammation of colon)
Death
Gallbladder oedema (swelling of gallbladder)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

40-49:

Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Abdominal pain upper
Chest discomfort
Chest pain
Chills (felling of cold)
Cholecystitis acute (rapid infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness

50-59:

Cough
Drug ineffective
Dry eye (lack of adequate tears)
Dyspnoea (difficult or laboured respiration)
Ear pain
Feeling jittery
Headache (pain in head)
Hypoxia (low oxygen in tissues)
International normalised ratio increased
Lung transplant rejection (failure of lung transplant)

60+:

Pain
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Neck pain
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Emotional disorder
Malaise (a feeling of general discomfort or uneasiness)
Chest pain
Injury
Multiple injuries

What are the existing conditions these people have? *

Atrial Tachycardia (rhythm disturbance that arises in the atria): 7 people, 17.07%
Pain: 5 people, 12.20%
Joint Pain: 5 people, 12.20%
High Blood Pressure: 5 people, 12.20%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 12.20%
Multiple Myeloma (cancer of the plasma cells): 4 people, 9.76%
High Blood Cholesterol: 4 people, 9.76%
Stress And Anxiety: 3 people, 7.32%
Pneumonia: 3 people, 7.32%
Muscle Spasms (muscle contraction): 3 people, 7.32%

* Approximation only. Some reports may have incomplete information.

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