Metoclopramide and Hydrocortone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metoclopramide (metoclopramide hydrochloride) and Hydrocortone (hydrocortisone acetate). Common drug interactions include alanine aminotransferase increased among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Metoclopramide and Hydrocortone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Metoclopramide?

Metoclopramide has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 81,263 Metoclopramide users. Check the latest studies of Metoclopramide.

What is Hydrocortone?

Hydrocortone has active ingredients of hydrocortisone acetate. It is often used in pain. eHealthMe is studying from 912 Hydrocortone users. Check the latest studies of Hydrocortone.

On Jul, 12, 2026

21 people who take Metoclopramide and Hydrocortone together, and have interactions are studied.

Metoclopramide and Hydrocortone drug interactions.

What are the common drug interactions of Metoclopramide and Hydrocortone, by gender? *:

female:

Alanine aminotransferase increased
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Bacterial infection
Blood alkaline phosphatase increased
Blood pressure decreased
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Encephalitis (inflammation of the brain)
Fatigue (feeling of tiredness)

male:

Renal failure (kidney dysfunction)
Abdominal compartment syndrome (increased pressure in abdomen)
Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
Lactic acidosis (low ph in body tissues)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Multi-organ failure (multisystem organ failure)
Pyrexia (fever)
Septic shock (shock due to blood infection)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Acute respiratory distress syndrome

What are the common drug interactions of Metoclopramide and Hydrocortone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Multi-organ failure (multisystem organ failure)
Septic shock (shock due to blood infection)
Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
Acute respiratory distress syndrome
Hepatic congestion (liver congestion)
Hypoxia (low oxygen in tissues)
Pyrexia (fever)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)

30-39:

n/a

40-49:

n/a

50-59:

Alanine aminotransferase increased
Anaemia (lack of blood)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Blood alkaline phosphatase increased
Blood bilirubin increased
Febrile neutropenia (fever with reduced white blood cells)
Joint abscess (pus in joints due to infection)
Malaise (a feeling of general discomfort or uneasiness)
Muscle haemorrhage (bleeding in muscle)
Platelet count decreased

60+:

Dyspnoea (difficult or laboured respiration)
Hyperkalaemia (damage to or disease of the kidney)
Cystitis (inflammation of the wall of the bladder)
Cytomegalovirus infection
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diarrhoea
Dizziness
Insomnia (sleeplessness)
Lower respiratory tract infection
Melaena (the passage of black, tarry stools)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 23.81%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 14.29%
Adverse Event: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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