Metrogel and Valium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metrogel (metronidazole) and Valium (diazepam). Common drug interactions include dehydration among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Metrogel and Valium. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Metrogel?

Metrogel has active ingredients of metronidazole. It is often used in rosacea. eHealthMe is studying from 2,819 Metrogel users. Check the latest studies of Metrogel.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.



On Jul, 17, 2026

39 people who take Metrogel and Valium together, and have interactions are studied.

Metrogel and Valium drug interactions.

What are the common drug interactions of Metrogel and Valium, by gender? *:

female:

  1. Dehydration (dryness resulting from the removal of water)
  2. Depression
  3. Disease recurrence
  4. Drug ineffective
  5. Drug toxicity
  6. Emotional disorder
  7. Foaming at mouth (excess saliva secretion)
  8. Gait disturbance
  9. Gastric disorder (disease of stomach)
  10. Gastrointestinal neoplasm (cancer tumour of digestive tract)

male:

  1. Drug hypersensitivity
  2. Vomiting
  3. Fungal skin infection
  4. Genital discomfort
  5. Glucose urine present
  6. Mobility decreased (ability to move is reduced)
  7. Nausea (feeling of having an urge to vomit)
  8. Pain
  9. Pneumonia
  10. Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Metrogel and Valium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Device occlusion
  2. Abdominal pain
  3. Confusional state
  4. Crying
  5. Depression
  6. Dizziness
  7. Emotional disorder
  8. Fatigue (feeling of tiredness)
  9. Headache (pain in head)
  10. Hyperhidrosis (abnormally increased sweating)

40-49:

  1. Thyroid cancer

50-59:

  1. Hyperglycaemia (high blood sugar)
  2. Hypoglycaemia (deficiency of glucose in the bloodstream)
  3. Hypomania (a mild form of mania, marked by elation and hyperactivity)
  4. Hypoxia (low oxygen in tissues)
  5. Inappropriate affect
  6. Loss of consciousness
  7. Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
  8. Mania (a state of abnormally elevated or irritable mood)
  9. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  10. Muscular weakness (muscle weakness)

60+:

  1. Fall
  2. Cough
  3. Asthenia (weakness)
  4. Burning sensation
  5. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  6. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  7. Diarrhoea
  8. Dizziness
  9. Dyspnoea (difficult or laboured respiration)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Pain: 6 people, 15.38%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 15.38%
  3. Sleep Disorder: 6 people, 15.38%
  4. Acne (skin problems that cause pimples): 3 people, 7.69%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 7.69%
  6. Diarrhea: 3 people, 7.69%
  7. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 7.69%
  8. Dry Skin: 3 people, 7.69%
  9. High Blood Cholesterol: 2 people, 5.13%
  10. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Metrogel and Valium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Metrogel and Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metrogel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metrogel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole and diazepam (the active ingredients of Metrogel and Valium, respectively), and Metrogel and Valium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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