Metronidazole and Fluoride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Metronidazole (metronidazole) and Fluoride (fluoride). Common drug interactions include pain among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Metronidazole and Fluoride. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

What is Fluoride?

Fluoride has active ingredients of fluoride. eHealthMe is studying from 2,301 Fluoride users. Check the latest studies of Fluoride.



On Jul, 14, 2026

44 people who take Metronidazole and Fluoride together, and have interactions are studied.

Metronidazole and Fluoride drug interactions.

What are the common drug interactions of Metronidazole and Fluoride, by gender? *:

female:

  1. Pain
  2. Nausea (feeling of having an urge to vomit)
  3. Rash
  4. Abdominal pain upper
  5. Flushing (the warm, red condition of human skin)
  6. Pruritus (severe itching of the skin)
  7. Memory impairment
  8. Migraine (headache)
  9. Nephrolithiasis (calculi in the kidneys)
  10. Asthenia (weakness)

male:

  1. Fall
  2. Hip fracture
  3. Dysphagia (a condition in which swallowing is difficult or painful)
  4. Rash
  5. Surgery
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. Neuropathy peripheral (surface nerve damage)
  8. Anxiety
  9. Bone density decreased
  10. Emotional distress

What are the common drug interactions of Metronidazole and Fluoride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  2. Acute respiratory distress syndrome
  3. Bone density decreased
  4. Breath odour
  5. Dyskinesia (abnormality or impairment of voluntary movement)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Haemorrhage (bleeding)
  8. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  9. Mouth ulceration (mouth ulcers)
  10. Osteomyelitis (infection of bone)

20-29:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Cough
  3. Ear infection
  4. Pneumonia
  5. Scoliosis (a medical condition in which a person's spine is curved from side to side)
  6. Sinusitis (inflammation of sinus)
  7. Skin infection
  8. Urticaria (rash of round, red welts on the skin that itch intensely)
  9. Haematochezia (passage of stools containing blood)
  10. Pain

30-39:

  1. Anxiety
  2. Bone density decreased
  3. Emotional distress
  4. Nephropathy (damage to or disease of a kidney)
  5. Pain
  6. Renal failure (kidney dysfunction)
  7. Tooth loss

40-49:

  1. Hysterectomy

50-59:

  1. Fall
  2. Hip fracture
  3. Neuropathy peripheral (surface nerve damage)
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  5. Anxiety
  6. Bone density decreased
  7. Emotional distress
  8. Exercise tolerance decreased
  9. Gait disturbance
  10. Osteopenia (a condition where bone mineral density is lower than normal)

60+:

  1. Therapeutic response unexpected
  2. Arthralgia (joint pain)
  3. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  4. Hot flush (sudden feelings of heat)
  5. Hyperhidrosis (abnormally increased sweating)
  6. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  7. Immune system disorder
  8. Ocular rosacea (redness, irritation or burning of the eyes)
  9. Pruritus (severe itching of the skin)
  10. Rosacea (a skin condition that causes facial redness)

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 9 people, 20.45%
  2. Pain: 9 people, 20.45%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 20.45%
  4. Insomnia (sleeplessness): 7 people, 15.91%
  5. Stress And Anxiety: 7 people, 15.91%
  6. Diabetes: 6 people, 13.64%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 13.64%
  8. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 6 people, 13.64%
  9. High Blood Pressure: 6 people, 13.64%
  10. Immunodeficiency Common Variable: 5 people, 11.36%

* Approximation only. Some reports may have incomplete information.

Do you take Metronidazole and Fluoride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Metronidazole and Fluoride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metronidazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Fluoride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metronidazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Fluoride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on metronidazole and fluoride (the active ingredients of Metronidazole and Fluoride, respectively), and Metronidazole and Fluoride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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