Micardis hct and Synthroid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micardis hct (hydrochlorothiazide; telmisartan) and Synthroid (levothyroxine sodium). Common drug interactions include aortic valve incompetence among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Micardis hct and Synthroid. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.

What is Micardis hct?

Micardis hct has active ingredients of hydrochlorothiazide; telmisartan. It is often used in high blood pressure. eHealthMe is studying from 1,094 Micardis hct users. Check the latest studies of Micardis hct.

What is Synthroid?

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. eHealthMe is studying from 249,202 Synthroid users. Check the latest studies of Synthroid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

71 people who take Micardis hct and Synthroid together, and have interactions are studied.

Micardis hct and Synthroid drug interactions.

What are the common drug interactions of Micardis Hct and Synthroid, by gender? *:

female:

Aortic valve incompetence
Dehydration (dryness resulting from the removal of water)
Dyspnoea (difficult or laboured respiration)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Fungal infection
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hypertensive crisis
Tremor (trembling or shaking movements in one or more parts of your body)
Abdominal hernia
Acute myocardial infarction (acute heart attack)

male:

Drug ineffective
Abdominal distension
Dizziness
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)
Headache (pain in head)
Impaired gastric emptying
Pain
Panic attack
Post procedural infection

What are the common drug interactions of Micardis Hct and Synthroid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Bowel movement irregularity
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Frustration (a form of poorly expressed anger)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Intervertebral disc protrusion (spinal disc protrusion)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Paralysis
Toothache (tooth pain)

30-39:

n/a

40-49:

Abdominal distension
Adrenal neoplasm (abnormal growth of adrenal gland)
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug ineffective
Epicondylitis (tennis elbow)
Fatigue (feeling of tiredness)
Headache (pain in head)
Impaired gastric emptying
Influenza like illness

50-59:

Therapeutic response unexpected
Weight decreased
Arthralgia (joint pain)
Cough
Dehydration (dryness resulting from the removal of water)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness
Drug ineffective
Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
Facial paralysis (loss of function of face muscle)

60+:

Fatigue (feeling of tiredness)
Dizziness
Cardiogenic shock (inadequate circulation of blood)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Respiratory failure (inadequate gas exchange by the respiratory system)
Shock haemorrhagic (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin due to excess bleeding)
Anxiety
Blood glucose increased
Chronic kidney disease
Decreased appetite

What are the existing conditions these people have? *

High Blood Cholesterol: 15 people, 21.13%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 15.49%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 14.08%
Diabetes: 10 people, 14.08%
Pain: 8 people, 11.27%
Stress And Anxiety: 6 people, 8.45%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 8.45%
Type 2 Diabetes: 5 people, 7.04%
Thyroid Diseases: 5 people, 7.04%
Drowsiness: 5 people, 7.04%

* Approximation only. Some reports may have incomplete information.

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