Micardis and Amitiza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micardis (telmisartan) and Amitiza (lubiprostone). Common drug interactions include muscle rigidity among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Micardis and Amitiza. It is created by eHealthMe based on reports of 77 people who take the same drugs from the FDA, and is updated regularly.

What is Micardis?

Micardis has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 27,605 Micardis users. Check the latest studies of Micardis.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 10,567 Amitiza users. Check the latest studies of Amitiza.

On Jul, 05, 2026

77 people who take Micardis and Amitiza together, and have interactions are studied.

What are the common drug interactions of Micardis and Amitiza, by gender? *:

female:

Muscle rigidity (muscle stiffness)
Otitis media (inflammation of the middle ear)
Pain in jaw
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Right ventricular failure (right half of the heart fails to work)
Crying
Cystitis (inflammation of the wall of the bladder)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Chest pain
Dyspepsia (indigestion)

male:

Nausea (feeling of having an urge to vomit)
Renal impairment (severely reduced kidney function)
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Pain
Cold sweat
Dehydration (dryness resulting from the removal of water)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Glomerular filtration rate decreased

What are the common drug interactions of Micardis and Amitiza, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Crying
Cystitis (inflammation of the wall of the bladder)
Grand mal convulsion (a type of generalized seizure that affects the entire brain)
Anaemia (lack of blood)
Arthralgia (joint pain)
Blood glucose increased
Blood prolactin increased
Interstitial lung disease
Muscle rigidity (muscle stiffness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

50-59:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Renal cancer (cancer of kidney)
Renal injury (kidney injury)
Chronic kidney disease
Hypokalaemia (low potassium)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Cataract (clouding of the lens inside the eye)
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

60+:

Nausea (feeling of having an urge to vomit)
White blood cell count decreased
Dehydration (dryness resulting from the removal of water)
Malaise (a feeling of general discomfort or uneasiness)
Coronary artery stenosis (narrowing of coronary artery)
Haemoglobin decreased
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Abdominal discomfort
Drug ineffective
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 18 people, 23.38%
Pain: 13 people, 16.88%
High Blood Cholesterol: 9 people, 11.69%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 7 people, 9.09%
Insomnia (sleeplessness): 7 people, 9.09%
Depression: 6 people, 7.79%
Gastritis (inflammation of stomach): 6 people, 7.79%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 6.49%
Diabetes: 5 people, 6.49%
Abdominal Discomfort: 5 people, 6.49%

* Approximation only. Some reports may have incomplete information.

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