Micardis and Cotrim drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Micardis (telmisartan) and Cotrim (sulfamethoxazole; trimethoprim). Common drug interactions include back pain among females and interstitial lung disease among males.
The phase IV clinical study analyzes what interactions people have when they take Micardis and Cotrim. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.
What is Micardis?
Micardis has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 27,605 Micardis users. Check the latest studies of Micardis.
What is Cotrim?
Cotrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 8,890 Cotrim users. Check the latest studies of Cotrim.
35 people who take Micardis and Cotrim together, and have interactions are studied.

What are the common drug interactions of Micardis and Cotrim, by gender? *:
female:
- Back pain
- Blood creatinine increased
- Blood lactate dehydrogenase increased
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- C-reactive protein increased
- Cardiomegaly (increased size of heart than normal)
- Cardiovascular disorder (heart diseases)
- Cellulitis (infection under the skin)
- Cervical cyst (mucus-filled cyst on the surface of the cervix)
- Chest discomfort
male:
- Interstitial lung disease
- Malignant melanoma in situ (early stage of cancer in melanocyte)
- Abscess (pus)
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood creatinine increased
- Blood phosphorus decreased
- Cataract (clouding of the lens inside the eye)
- Chills (felling of cold)
- Chronic allograft nephropathy (failure of kidney transplant)
What are the common drug interactions of Micardis and Cotrim, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Urinary tract infection
- Acute tonsillitis
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dental caries
- Dermatitis allergic (inflammation of the skin due allergic reaction)
- Dizziness
- Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Gastroenteritis (inflammation of stomach and intestine)
- Gingival bleeding (bleeding gums)
30-39:
- Renal disorder (kidney disease)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Upper respiratory tract inflammation
- Urticaria (rash of round, red welts on the skin that itch intensely)
- Wound decomposition
- Abscess (pus)
- Blood creatinine increased
- Cataract (clouding of the lens inside the eye)
- Chronic allograft nephropathy (failure of kidney transplant)
- Dermal cyst
40-49:
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Diarrhoea
- Renal vessel disorder (disease of kidney vessel)
- Urinary tract infection
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Blood creatinine increased
- Blood lactate dehydrogenase increased
- Cardiovascular disorder (heart diseases)
- Dehydration (dryness resulting from the removal of water)
50-59:
- Cataract (clouding of the lens inside the eye)
- Dermal cyst
- Headache (pain in head)
- Infection
- Nasopharyngitis (inflammation of the nasopharynx)
- Nervousness
- Neutropenia (an abnormally low number of neutrophils)
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
- Tremor (trembling or shaking movements in one or more parts of your body)
60+:
- Interstitial lung disease
- Malignant melanoma in situ (early stage of cancer in melanocyte)
- Blood alkaline phosphatase increased
- Blood bilirubin increased
- Blood phosphorus decreased
- C-reactive protein increased
- Constipation
- Dermal cyst
- Diarrhoea
- Disease progression
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 10 people, 28.57%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 20.00%
- Sleep Disorder: 6 people, 17.14%
- Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 6 people, 17.14%
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 14.29%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 5.71%
- Rickets (softening of bones): 2 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Micardis and Cotrim?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Micardis and Cotrim:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Micardis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Cotrim:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Micardis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cotrim and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on telmisartan and sulfamethoxazole; trimethoprim (the active ingredients of Micardis and Cotrim, respectively), and Micardis and Cotrim (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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