Micardis and Elavil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Micardis (telmisartan) and Elavil (amitriptyline hydrochloride). Common drug interactions include nausea among females and fatigue among males.
The phase IV clinical study analyzes what interactions people have when they take Micardis and Elavil. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Micardis?
Micardis has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 27,605 Micardis users. Check the latest studies of Micardis.
What is Elavil?
Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 20,724 Elavil users. Check the latest studies of Elavil.
61 people who take Micardis and Elavil together, and have interactions are studied.

What are the common drug interactions of Micardis and Elavil, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Pain
- Anxiety
- Arthralgia (joint pain)
- Back pain
- Constipation
- Gait disturbance
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gingival ulceration (ulcer on gums)
- Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
male:
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Cerebral atrophy (decrement in size of brain)
- Decreased appetite
- Diarrhoea
- Exostosis (formation of new bone on the surface of a bone)
- Oedema peripheral (superficial swelling)
- Pain
- Pain in extremity
- Anxiety
What are the common drug interactions of Micardis and Elavil, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Asthma
- Pancreatitis acute (sudden inflammation of pancreas)
- Pharyngeal erythema (pharyngeal redness)
- Rhinitis allergic (inflammation of the nasal airways due to allergy)
40-49:
- Chest pain
- Dyspnoea (difficult or laboured respiration)
- Drug ineffective
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Blood cholesterol increased
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Death
50-59:
- Spinal osteoarthritis (joint cartilage loss in spine)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tongue ulceration (ulcers on tongue)
- Arthralgia (joint pain)
- Bone disorder
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Osteoporosis (bones weak and more likely to break)
- Pain in jaw
- Abdominal pain upper
- Back pain
60+:
- Pain in extremity
- Fatigue (feeling of tiredness)
- Decreased appetite
- Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
- Diarrhoea
- Fall
- Impaired healing
- Vomiting
- Weight decreased
- Foot deformity (functional disability of foot)
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 11 people, 18.03%
- Pain: 10 people, 16.39%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 16.39%
- Diabetes: 10 people, 16.39%
- Metastases To Bone (cancer spreads to bone): 7 people, 11.48%
- Chest Pain: 7 people, 11.48%
- Back Pain: 7 people, 11.48%
- Nausea (feeling of having an urge to vomit): 5 people, 8.20%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 8.20%
- Joint Pain: 5 people, 8.20%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Micardis and Elavil:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Micardis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Elavil:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Micardis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Elavil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on telmisartan and amitriptyline hydrochloride (the active ingredients of Micardis and Elavil, respectively), and Micardis and Elavil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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