Micardis and Inspra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Micardis (telmisartan) and Inspra (eplerenone). Common drug interactions include myalgia among females and myalgia among males.
The phase IV clinical study analyzes what interactions people have when they take Micardis and Inspra. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Micardis?
Micardis has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 27,605 Micardis users. Check the latest studies of Micardis.
What is Inspra?
Inspra has active ingredients of eplerenone. It is often used in high blood pressure. eHealthMe is studying from 3,510 Inspra users. Check the latest studies of Inspra.
20 people who take Micardis and Inspra together, and have interactions are studied.

What are the common drug interactions of Micardis and Inspra, by gender? *:
female:
- Myalgia (muscle pain)
- Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Neck pain
- Neurological symptom (symptoms of nervous system disease)
- Neuropathy peripheral (surface nerve damage)
- Obesity (having too much body fat)
- Oral herpes (viral infection of mouth)
- Panic attack
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
male:
- Myalgia (muscle pain)
- Decreased interest
- Renal failure acute (rapid kidney dysfunction)
- Local swelling (swelling at the site of some application of substance or injury)
- Tinnitus (a ringing in the ears)
- Blood cholesterol increased
- Cardiac disorder
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Fatigue (feeling of tiredness)
- Hypersensitivity
What are the common drug interactions of Micardis and Inspra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Neurological symptom (symptoms of nervous system disease)
- Neuropathy peripheral (surface nerve damage)
- Obesity (having too much body fat)
- Oral herpes (viral infection of mouth)
- Panic attack
- Pharyngitis (inflammation of the pharynx, causing a sore throat)
- Plantar fasciitis (painful inflammatory process of the plantar fascia)
- Presyncope
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Syncope (loss of consciousness with an inability to maintain postural tone)
50-59:
- Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Mitral valve incompetence (inefficient heart valve)
- Tricuspid valve incompetence (inefficient heart valve)
60+:
- Myalgia (muscle pain)
- Blood creatine phosphokinase increased
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Tuberculosis (a bacterial infection by mycobacterium tuberculosis)
- Aortic dilatation
- Cardiomegaly (increased size of heart than normal)
- Decreased interest
- Dermo-hypodermitis (skin and subcutaneous tissue bacterial infections)
- Disturbance in attention
- Dizziness
What are the existing conditions these people have? *
- Cardiac Disorder: 6 people, 30.00%
- Gout (uric acid crystals building up in the body): 3 people, 15.00%
- Staphylococcal Sepsis (blood infection by an infection with staphylococcus bacteria): 2 people, 10.00%
- High Blood Cholesterol: 2 people, 10.00%
- Congestive Cardiomyopathy (weakening of heart muscle): 2 people, 10.00%
- Cardiac Failure: 2 people, 10.00%
- Ill-Defined Disorder: 1 person, 5.00%
- Hyperaldosteronism: 1 person, 5.00%
- Heart Disease: 1 person, 5.00%
- Enlarged Prostate: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Micardis and Inspra?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Micardis and Inspra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Micardis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Inspra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Micardis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Inspra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on telmisartan and eplerenone (the active ingredients of Micardis and Inspra, respectively), and Micardis and Inspra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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