Micardis and Tekturna drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Micardis (telmisartan) and Tekturna (aliskiren hemifumarate). Common drug interactions include pruritus among females and vision blurred among males.
The phase IV clinical study analyzes what interactions people have when they take Micardis and Tekturna. It is created by eHealthMe based on reports of 92 people who take the same drugs from the FDA, and is updated regularly.
What is Micardis?
Micardis has active ingredients of telmisartan. It is often used in high blood pressure. eHealthMe is studying from 27,605 Micardis users. Check the latest studies of Micardis.
What is Tekturna?
Tekturna has active ingredients of aliskiren hemifumarate. It is often used in high blood pressure. eHealthMe is studying from 4,730 Tekturna users. Check the latest studies of Tekturna.
92 people who take Micardis and Tekturna together, and have interactions are studied.

What are the common drug interactions of Micardis and Tekturna, by gender? *:
female:
- Pruritus (severe itching of the skin)
- Alopecia (absence of hair from areas of the body)
- Asthenia (weakness)
- Gait disturbance
- Renal failure (kidney dysfunction)
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Arthralgia (joint pain)
- Feeling of body temperature change
- Hypoaesthesia (reduced sense of touch or sensation)
male:
- Vision blurred
- Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
- Angioedema (rapid swelling of the dermis)
- Dizziness
- Drug ineffective
- Flatulence (flatus expelled through the anus)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hypotension (abnormally low blood pressure)
- Influenza
- Malaise (a feeling of general discomfort or uneasiness)
What are the common drug interactions of Micardis and Tekturna, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Pancreatitis (inflammation of pancreas)
- Papillary thyroid cancer
- Post procedural hypothyroidism
- Toxic nodular goitre (a thyroid gland that contains autonomously functioning thyroid nodules, with resulting excess thyroid hormone secretion)
40-49:
- Cardiac disorder
- Chest pain
- Drug ineffective
- Heart rate increased
- Oedema peripheral (superficial swelling)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fatigue (feeling of tiredness)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Chest discomfort
50-59:
- Hemiparesis (weakness on one side of the body)
- Hospitalisation
- Muscular weakness (muscle weakness)
- Obesity (having too much body fat)
- Oedema peripheral (superficial swelling)
- Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
- Post procedural haemorrhage (post procedural bleeding)
- Proteinuria (presence of protein in the urine)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Rheumatic fever (an inflammatory disease that occurs following a streptococcus pyogenes infection)
60+:
- Pruritus (severe itching of the skin)
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Rash
- Agitation (state of anxiety or nervous excitement)
- Anxiety
- Arthralgia (joint pain)
- Constipation
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Feeling of body temperature change
- Hypersensitivity
What are the existing conditions these people have? *
- Multiple Myeloma (cancer of the plasma cells): 7 people, 7.61%
- Immunodeficiency Common Variable: 6 people, 6.52%
- High Blood Cholesterol: 5 people, 5.43%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 5.43%
* Approximation only. Some reports may have incomplete information.
Do you take Micardis and Tekturna?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Micardis and Tekturna:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Micardis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tekturna:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Micardis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tekturna and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
- Kato Y, Mukai Y, Rane A, Inotsume N, Toda T, "The inhibitory effect of telmisartan on the metabolism of arachidonic acid by CYP2C9 and CYP2C8: an in vitro study", Biological and Pharmaceutical Bulletin, 2017 Sep .
- Kim HK, Youm JB, Lee SR, Lim SE, Lee SY, Ko TH, Nilius B, Noh JH, Ko KS, Rhee BD, Kim N, "The angiotensin receptor blocker and PPAR-γ agonist, telmisartan, delays inactivation of voltage-gated sodium channel in rat heart: novel mechanism of drug action", Pflügers Archiv-European Journal of Physiology, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on telmisartan and aliskiren hemifumarate (the active ingredients of Micardis and Tekturna, respectively), and Micardis and Tekturna (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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