Micronor and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Micronor (norethindrone) and Profen (ibuprofen). Common drug interactions include anxiety among females.

The phase IV clinical study analyzes what interactions people have when they take Micronor and Profen. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.

What is Micronor?

Micronor has active ingredients of norethindrone. It is often used in birth control. eHealthMe is studying from 1,344 Micronor users. Check the latest studies of Micronor.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 28, 2026

65 people who take Micronor and Profen together, and have interactions are studied.

What are the common drug interactions of Micronor and Profen, by gender? *:

female:

Anxiety
Dyspnoea (difficult or laboured respiration)
Injection site erythema (redness at injection site)
Injection site haematoma (localized swelling filled with blood at injection site)
Injection site pain
Mononucleosis syndrome (an infection that produces flu-like symptoms, and usually goes away on its own in a few weeks)
Oedema peripheral (superficial swelling)
Influenza
Pharyngitis streptococcal (inflammation of the pharynx caused by infection from. streptococcus)
Emotional distress

male:

n/a

What are the common drug interactions of Micronor and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal pain
Cholecystitis chronic (long lasting infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Fear
Hallucination (an experience involving the perception of something not present)
Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Muscular weakness (muscle weakness)

20-29:

Anxiety
Dyspnoea (difficult or laboured respiration)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Injection site erythema (redness at injection site)
Injection site haematoma (localized swelling filled with blood at injection site)
Injection site pain
Mononucleosis syndrome (an infection that produces flu-like symptoms, and usually goes away on its own in a few weeks)
Pulmonary embolism (blockage of the main artery of the lung)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)

30-39:

Renal failure acute (rapid kidney dysfunction)
Urinary tract infection
Vision blurred
Weight decreased
Headache (pain in head)
Alopecia (absence of hair from areas of the body)
Chlamydial infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis)
Constipation
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)

40-49:

Anxiety
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Headache (pain in head)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Abdominal discomfort
Anaemia (lack of blood)
Arthralgia (joint pain)
Aspartate aminotransferase decreased

50-59:

Burning sensation
Cough
Urticaria (rash of round, red welts on the skin that itch intensely)
Angioedema (rapid swelling of the dermis)
Dyspepsia (indigestion)
Breast cancer
Erythema multiforme (a type of hypersensitivity reaction)
Hypersensitivity
Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)

60+:

n/a

What are the existing conditions these people have? *

Headache (pain in head): 10 people, 15.38%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.85%
Stress And Anxiety: 6 people, 9.23%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 5 people, 7.69%
Muscle Spasms (muscle contraction): 5 people, 7.69%
Itching: 5 people, 7.69%
Infection: 5 people, 7.69%
Vaginal Bleeding: 4 people, 6.15%
Dysmenorrhea (painful menstruation): 4 people, 6.15%
Constipation: 4 people, 6.15%

* Approximation only. Some reports may have incomplete information.

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