Microzide and Centrum silver drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Microzide (hydrochlorothiazide) and Centrum silver (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include blood potassium decreased among females.
The phase IV clinical study analyzes what interactions people have when they take Microzide and Centrum silver. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Microzide?
Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.
What is Centrum silver?
Centrum silver has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 19,997 Centrum silver users. Check the latest studies of Centrum silver.
11 people who take Microzide and Centrum silver together, and have interactions are studied.

What are the common drug interactions of Microzide and Centrum Silver, by gender? *:
female:
- Blood potassium decreased
- Metastases to lymph nodes (cancer spreads to lymph node)
- Disease progression
- Drug ineffective
- Laryngitis (inflammation of the larynx)
- Metastases to bone (cancer spreads to bone)
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
- Obesity (having too much body fat)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pruritus (severe itching of the skin)
male:
n/a
What are the common drug interactions of Microzide and Centrum Silver, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
- Arthralgia (joint pain)
- Breast cancer female
- Drug ineffective
- Metastases to bone (cancer spreads to bone)
- Metastases to lymph nodes (cancer spreads to lymph node)
- Muscle spasms (muscle contraction)
- Obesity (having too much body fat)
- Pulmonary mass
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
60+:
- Blood potassium decreased
- Breast cancer
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Pruritus (severe itching of the skin)
- Sinusitis (inflammation of sinus)
- Tongue disorder (disease of tongue)
- Breast cancer metastatic
- Decreased interest
- Depressed mood
- Disease progression
What are the existing conditions these people have? *
- Hyperkalemia (damage to or disease of the kidney): 3 people, 27.27%
- Breast Cancer: 3 people, 27.27%
- Psychotic Disorder: 1 person, 9.09%
- Pain: 1 person, 9.09%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
- Movement - Uncoordinated: 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Microzide and Centrum silver?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Microzide (994 reports)
- Centrum silver (19,997 reports)
Browse all drug interactions of Microzide and Centrum silver:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Microzide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Centrum silver:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Microzide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Centrum silver and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Microzide and Centrum silver, respectively), and Microzide and Centrum silver (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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