Microzide and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Microzide (hydrochlorothiazide) and Oxycodone (oxycodone hydrochloride). Common drug interactions include blood glucose decreased among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Microzide and Oxycodone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Microzide?

Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

On Jul, 25, 2026

21 people who take Microzide and Oxycodone together, and have interactions are studied.

Microzide and Oxycodone drug interactions.

What are the common drug interactions of Microzide and Oxycodone, by gender? *:

female:

Blood glucose decreased
Bone cyst
Fatigue (feeling of tiredness)
Rash pruritic (redness with itching)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Full blood count decreased
Gait disturbance
Headache (pain in head)
Infection
Joint swelling

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Diarrhoea
Gangrene (body tissue dies)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypotension (abnormally low blood pressure)
Pneumonia
Pulmonary congestion (congestion in the lungs)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

What are the common drug interactions of Microzide and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Gait disturbance
Joint swelling
Pain in extremity

50-59:

Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Full blood count decreased
Infection
Palpitations (feelings or sensations that your heart is pounding or racing)
Pruritus (severe itching of the skin)
Pyrexia (fever)

60+:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Pneumonia
Pulmonary congestion (congestion in the lungs)
Pyrexia (fever)
Renal failure (kidney dysfunction)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

What are the existing conditions these people have? *

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 4 people, 19.05%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 19.05%
Multiple Myeloma (cancer of the plasma cells): 3 people, 14.29%
Sleep Disorder: 2 people, 9.52%
Neuropathy Peripheral (surface nerve damage): 2 people, 9.52%
Enlarged Prostate: 2 people, 9.52%
Diabetes: 2 people, 9.52%
Cardiac Disorder: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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