Microzide and Prinivil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Microzide (hydrochlorothiazide) and Prinivil (lisinopril). Common drug interactions include malaise among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Microzide and Prinivil. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Microzide?

Microzide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 994 Microzide users. Check the latest studies of Microzide.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. eHealthMe is studying from 20,152 Prinivil users. Check the latest studies of Prinivil.

On Jul, 15, 2026

39 people who take Microzide and Prinivil together, and have interactions are studied.

Microzide and Prinivil drug interactions.

What are the common drug interactions of Microzide and Prinivil, by gender? *:

female:

Malaise (a feeling of general discomfort or uneasiness)
Cardiac failure congestive
Dyspnoea (difficult or laboured respiration)
Vitamin d deficiency
Bradycardia (abnormally slow heart action)
Cough
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

Death
Adenosquamous cell lung cancer (mixed cell lung cancer)
Heart rate increased
Heart rate irregular
Low density lipoprotein decreased (cholesterol decreased)
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
Myalgia (muscle pain)
Pain in extremity
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Radiation injury (injuries are caused by radiation)

What are the common drug interactions of Microzide and Prinivil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Cardiac failure
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Impaired work ability
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Pain
Pericardial effusion (fluid around the heart)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

50-59:

Dyspnoea (difficult or laboured respiration)
Vitamin d deficiency
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Cardiac failure congestive
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cough
Ejection fraction decreased (systolic heart failure)

60+:

Dizziness
Drug ineffective
Chronic kidney disease
Colon adenoma (non cancerous epithelial colon tumour having a glandular origin and structure)
Confusional state
Constipation
Cough
Disease progression
Drug hypersensitivity
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 17.95%
High Blood Cholesterol: 6 people, 15.38%
Diabetes: 6 people, 15.38%
Type 2 Diabetes: 5 people, 12.82%
Pain: 5 people, 12.82%
Blood Pressure Abnormal: 5 people, 12.82%
Diarrhea: 5 people, 12.82%
Immunodeficiency Disorders: 4 people, 10.26%
Hypotension (abnormally low blood pressure): 4 people, 10.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 10.26%

* Approximation only. Some reports may have incomplete information.

Do you take Microzide and Prinivil?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously