Thiotepa and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Thiotepa (thiotepa) and Acetaminophen (acetaminophen). Common drug interactions include gingival disorder among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Thiotepa and Acetaminophen. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Thiotepa?

Thiotepa has active ingredients of thiotepa. eHealthMe is studying from 8,097 Thiotepa users. Check the latest studies of Thiotepa.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 15, 2026

47 people who take Thiotepa and Acetaminophen together, and have interactions are studied.

Thiotepa and Acetaminophen drug interactions.

What are the common drug interactions of Thiotepa and Acetaminophen, by gender? *:

female:

Gingival disorder (gum disease)
Gingival oedema (swelling of gums)
Gingival swelling (gums swelling)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Haematoma (collection of blood outside the blood vessels)
Hepatic steatosis (fatty liver disease)
Hilar lymphadenopathy (disease of the lymph nodes due to infection)
Hot flush (sudden feelings of heat)
Hypertension (high blood pressure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

male:

Febrile neutropenia (fever with reduced white blood cells)
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Abdominal pain
Alopecia (absence of hair from areas of the body)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Candidiasis (candidiasis or thrush is a fungal infection)
Cardiac arrest
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Diarrhoea
Failure to thrive (inadequate weight gain and physical growth in children)

What are the common drug interactions of Thiotepa and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Mucosal inflammation (infection of mucous membrane)
Abdominal distension
Alopecia (absence of hair from areas of the body)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Candidiasis (candidiasis or thrush is a fungal infection)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid overload (too much fluid in the blood)
Gastroenteritis (inflammation of stomach and intestine)

2-9:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Endocrine disorder (endocrine diseases are disorders of the endocrine system)
Mucosal inflammation (infection of mucous membrane)
Venoocclusive disease (small veins in the liver are obstructed)
Bacterial sepsis
Cytomegalovirus infection
Diarrhoea
Idiopathic pneumonia syndrome (pneumonia-like symptoms)
Liver disorder (liver diseases)

10-19:

n/a

20-29:

Cardiac arrest
Diarrhoea
Enteritis (inflammation of the small intestine)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Mucosal inflammation (infection of mucous membrane)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)

30-39:

n/a

40-49:

Atelectasis (partial or complete collapse of the lung)
Bone disorder
Bone formation increased
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bruxism (habitual grinding of the teeth, typically during sleep)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Cough
Depression
Disease progression
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)

50-59:

n/a

60+:

Febrile neutropenia (fever with reduced white blood cells)
Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
Parainfluenzae virus infection
Systemic candida (whole body fungal infection)

What are the existing conditions these people have? *

Bone Marrow Conditioning Regimen: 16 people, 34.04%
Primitive Neuroectodermal Tumor: 5 people, 10.64%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 5 people, 10.64%
Burkitt Lymphoma (cancer of the lymphatic system): 5 people, 10.64%
Diffuse Large B-Cell Lymphoma Stage Iv (cancer of b cells, a type of white blood cell-stage iv): 4 people, 8.51%
Bone Marrow Failure: 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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