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Midazolam and Keflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midazolam (midazolam) and Keflex (cephalexin). Common drug interactions include haematuria among females and atrial fibrillation among males.

The phase IV clinical study analyzes what interactions people have when they take Midazolam and Keflex. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

On Jul, 26, 2026

25 people who take Midazolam and Keflex together, and have interactions are studied.

Midazolam and Keflex drug interactions.

What are the common drug interactions of Midazolam and Keflex, by gender? *:

female:

  1. Haematuria (presence of blood in urine)
  2. Haemoglobin decreased
  3. Headache (pain in head)
  4. Heart rate increased
  5. Hypoacusis (loss of hearing)
  6. Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
  7. Hypokinesia (decreased bodily movement)
  8. Influenza
  9. Influenza like illness
  10. Infusion related reaction

male:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Neutropenia (an abnormally low number of neutrophils)
  3. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  4. Obesity (having too much body fat)
  5. Osteopenia (a condition where bone mineral density is lower than normal)
  6. Pain
  7. Perineal abscess
  8. Renal failure (kidney dysfunction)
  9. Scrotal abscess (pus in scrotum)
  10. Subcutaneous abscess

What are the common drug interactions of Midazolam and Keflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Depression
  4. Emotional distress
  5. Fracture
  6. Fractured sacrum
  7. Gait disturbance
  8. Hip fracture
  9. Joint dislocation (a joint position is changed from normal position)
  10. Joint injury

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Fascial infection (infection in muscle surrounding tissue)
  5. Folliculitis (infection of hair root)
  6. Groin abscess (pus in groin)
  7. Hyperglycaemia (high blood sugar)
  8. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  9. Hypertension (high blood pressure)
  10. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

50-59:

  1. Perioral dermatitis (facial rash that causes bumps to develop around the mouth)
  2. Psoriasis (immune-mediated disease that affects the skin)
  3. Sacroiliitis (an inflammation of the sacroiliac joint)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
  6. Vulval abscess
  7. Bone loss
  8. Chronic kidney disease
  9. Drug resistance (reduction in effectiveness of a drug)
  10. Fracture

60+:

  1. Pyrexia (fever)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Balance disorder
  4. Bladder pain
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Blood iron decreased
  7. Blood pressure increased
  8. Blood pressure systolic increased
  9. Blood urine present
  10. Body temperature increased

What are the existing conditions these people have? *

  1. Asthma: 5 people, 20.00%
  2. Type 2 Diabetes: 5 people, 20.00%
  3. Weight Decreased: 4 people, 16.00%
  4. Hiv Infection: 4 people, 16.00%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.00%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 12.00%
  7. Hypotension (abnormally low blood pressure): 3 people, 12.00%
  8. Hypersensitivity: 3 people, 12.00%
  9. Pain: 3 people, 12.00%
  10. Diabetes: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Midazolam and Keflex?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Midazolam and Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Midazolam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Keflex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Midazolam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Keflex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on midazolam and cephalexin (the active ingredients of Midazolam and Keflex, respectively), and Midazolam and Keflex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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