Midazolam and Lantus drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midazolam (midazolam) and Lantus (insulin glargine recombinant). Common drug interactions include cellulitis gangrenous among females and thrombocytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Midazolam and Lantus. It is created by eHealthMe based on reports of 89 people who take the same drugs from the FDA, and is updated regularly.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

What is Lantus?

Lantus has active ingredients of insulin glargine recombinant. It is often used in diabetes. eHealthMe is studying from 191,782 Lantus users. Check the latest studies of Lantus.

On Aug, 01, 2026

89 people who take Midazolam and Lantus together, and have interactions are studied.

What are the common drug interactions of Midazolam and Lantus, by gender? *:

female:

Cellulitis gangrenous (localized inflammation of the soft or connective tissue with considerable mass of body tissue dies (necrosis))
Gangrene (body tissue dies)
Vulvitis (inflammation of the vulva)
Abscess (pus)
Acute hepatic failure
Pyrexia (fever)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood pressure decreased
Burkholderia test positive
Cough

male:

Thrombocytopenia (decrease of platelets in blood)
Renal failure (kidney dysfunction)
Syncope (loss of consciousness with an inability to maintain postural tone)
Alanine aminotransferase increased
Asthenia (weakness)
Bacteraemia (presence of bacteria in the blood)
Platelet count decreased
Pneumonia bacterial (pneumonia associated with bacterial infection)
Pyrexia (fever)
Urinary tract infection

What are the common drug interactions of Midazolam and Lantus, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Propofol infusion syndrome
Pyrexia (fever)

20-29:

n/a

30-39:

Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Thrombocytopenia (decrease of platelets in blood)

40-49:

Sepsis (a severe blood infection that can lead to organ failure and death)
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Cellulitis (infection under the skin)
Perineal abscess
Anal abscess
Vulval abscess
Vulval cellulitis (inflammation of skin around vagina)
Urinary tract infection
Nerve injury
Pain

50-59:

Blood creatinine increased
Bone abscess
Cardiac arrest
Cardiac failure
Death
Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
Fibrin d dimer increased
Fungal infection
Gait disturbance
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

60+:

Thrombocytopenia (decrease of platelets in blood)
Cardiac arrest
Agitation (state of anxiety or nervous excitement)
Blood alkaline phosphatase increased
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Diarrhoea
Enterobacter infection (infection caused by bacteria of the family enterobacteriaceae)
Escherichia infection (bacterial infection by escherichia coli)
Hyperglycaemia (high blood sugar)
Hypoglycaemia (deficiency of glucose in the bloodstream)

What are the existing conditions these people have? *

Constipation: 27 people, 30.34%
Nausea (feeling of having an urge to vomit): 26 people, 29.21%
Type 2 Diabetes: 24 people, 26.97%
Sedation: 22 people, 24.72%
High Blood Pressure: 18 people, 20.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 17 people, 19.10%
Pain: 16 people, 17.98%
Hypotension (abnormally low blood pressure): 16 people, 17.98%
Weight Decreased: 14 people, 15.73%
Hyperkalemia (damage to or disease of the kidney): 14 people, 15.73%

* Approximation only. Some reports may have incomplete information.

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