Midazolam and Pemetrexed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midazolam (midazolam) and Pemetrexed (pemetrexed). Common drug interactions include pyrexia among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Midazolam and Pemetrexed. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

What is Pemetrexed?

Pemetrexed has active ingredients of pemetrexed. eHealthMe is studying from 17,491 Pemetrexed users. Check the latest studies of Pemetrexed.

On Jul, 18, 2026

51 people who take Midazolam and Pemetrexed together, and have interactions are studied.

Midazolam and Pemetrexed drug interactions.

What are the common drug interactions of Midazolam and Pemetrexed, by gender? *:

female:

Pyrexia (fever)
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Oesophagitis (inflammation of oesophagus)
Abdominal pain
Cough
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Anaemia (lack of blood)
Death

male:

Interstitial lung disease
Respiratory distress (difficulty in breathing)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Nephropathy toxic (damage to kidney due to toxins)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Acute respiratory distress syndrome
Colitis (inflammation of colon)
Confusional state
Hepatic failure (liver failure)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

What are the common drug interactions of Midazolam and Pemetrexed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Colitis (inflammation of colon)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)

50-59:

Oesophagitis (inflammation of oesophagus)
Bronchostenosis (narrowing of a bronchial tube by scarring or other stricture)
Pneumonia
Colitis (inflammation of colon)
Confusional state
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Skin toxicity (skin damage due to toxin/poison)
Syncope (loss of consciousness with an inability to maintain postural tone)

60+:

Pyrexia (fever)
Febrile neutropenia (fever with reduced white blood cells)
Death
Pneumonia
Platelet count decreased
Myocarditis (inflammation of heart muscle myocardium)
Respiratory failure (inadequate gas exchange by the respiratory system)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 16 people, 31.37%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 13 people, 25.49%
Neoplasm Malignant (cancer tumour): 12 people, 23.53%
Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 10 people, 19.61%
Cough: 10 people, 19.61%
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 10 people, 19.61%
Nausea (feeling of having an urge to vomit): 8 people, 15.69%
Infection: 8 people, 15.69%
Pain: 8 people, 15.69%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 8 people, 15.69%

* Approximation only. Some reports may have incomplete information.

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