Midazolam and Soliris drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midazolam (midazolam) and Soliris (eculizumab). Common drug interactions include aplastic anaemia among females and acute respiratory failure among males.

The phase IV clinical study analyzes what interactions people have when they take Midazolam and Soliris. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Midazolam?

Midazolam has active ingredients of midazolam. eHealthMe is studying from 11,246 Midazolam users. Check the latest studies of Midazolam.

What is Soliris?

Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.

On Jul, 17, 2026

13 people who take Midazolam and Soliris together, and have interactions are studied.

Midazolam and Soliris drug interactions.

What are the common drug interactions of Midazolam and Soliris, by gender? *:

female:

Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
Death
Herpes zoster
Renal failure (kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Acute respiratory failure
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Encephalitis autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain)
Renal cancer metastatic (cancer of kidney spreads to other part)
Septic shock (shock due to blood infection)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)

What are the common drug interactions of Midazolam and Soliris, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Acute respiratory failure
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Diarrhoea
Hepatic enzyme increased
Nausea (feeling of having an urge to vomit)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Respiratory distress (difficulty in breathing)
Venoocclusive liver disease (small veins in the liver are obstructed)
Vomiting
Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Respiratory failure (inadequate gas exchange by the respiratory system)
Herpes zoster
Complement factor increased
Encephalitis autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain)
Septic shock (shock due to blood infection)
Renal failure (kidney dysfunction)

50-59:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Intravascular haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve incompetence (inefficient heart valve)
Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)

60+:

n/a

What are the existing conditions these people have? *

Thrombotic Microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury): 2 people, 15.38%
Swallowing Pain Or Burning: 2 people, 15.38%
Pressure Ulcer: 2 people, 15.38%
Diarrhea: 2 people, 15.38%
Cytomegalovirus Infection: 2 people, 15.38%
Constipation: 2 people, 15.38%
Venoocclusive Disease (small veins in the liver are obstructed): 1 person, 7.69%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 7.69%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 7.69%
Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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