Midol and Pantoprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Midol (ibuprofen) and Pantoprazole (pantoprazole sodium). Common drug interactions include headache among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Midol and Pantoprazole. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Midol?

Midol has active ingredients of ibuprofen. It is often used in painful menstrual periods. eHealthMe is studying from 2,635 Midol users. Check the latest studies of Midol.

What is Pantoprazole?

Pantoprazole has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 285,165 Pantoprazole users. Check the latest studies of Pantoprazole.

On Jul, 13, 2026

29 people who take Midol and Pantoprazole together, and have interactions are studied.

Midol and Pantoprazole drug interactions.

What are the common drug interactions of Midol and Pantoprazole, by gender? *:

female:

Headache (pain in head)
Dehydration (dryness resulting from the removal of water)
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Vision blurred
Depression
Dizziness
Drug ineffective
Flushing (the warm, red condition of human skin)

male:

Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Aphasia (damage to the parts of the brain that control language)
Blood urine present
Cerebral artery thrombosis (clot formation in brain blood vessels)
Depression
Hemiplegia (paralysis of one side of the body)
Injury
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Malignant neoplasm progression (cancer tumour came back)

What are the common drug interactions of Midol and Pantoprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Depression
Dizziness
Insomnia (sleeplessness)
Migraine (headache)
Nausea (feeling of having an urge to vomit)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Suicidal ideation
Vision blurred

30-39:

Irritability
Renal injury (kidney injury)
Blood glucose decreased
Body temperature increased
Chronic kidney disease
Feeling hot
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Headache (pain in head)
Hyperacusis (disorder in loudness perception)
Influenza like illness

40-49:

Headache (pain in head)
Flushing (the warm, red condition of human skin)
Abdominal discomfort
Abdominal pain
Diarrhoea
Hepatic enzyme increased
Hypersensitivity
Nausea (feeling of having an urge to vomit)

50-59:

Blood creatinine increased
Blood potassium increased
Blood urea increased
Cardiac failure
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Localised oedema (fluid retention in a particular part of the body)
Oedema peripheral (superficial swelling)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aphasia (damage to the parts of the brain that control language)
Vision blurred
Blood urine present
Cerebral artery thrombosis (clot formation in brain blood vessels)
Depression
Hemiplegia (paralysis of one side of the body)
Injury
Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain)
Pain

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 34.48%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 34.48%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 20.69%
Birth Control: 3 people, 10.34%
Pain: 3 people, 10.34%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Depression: 3 people, 10.34%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 10.34%
Hypersensitivity: 3 people, 10.34%
Vitamin C Decreased: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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