Minipress and Restoril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minipress (prazosin hydrochloride) and Restoril (temazepam). Common drug interactions include vomiting among females and blood triglycerides increased among males.

The phase IV clinical study analyzes what interactions people have when they take Minipress and Restoril. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Minipress?

Minipress has active ingredients of prazosin hydrochloride. It is often used in post-traumatic stress disorder. eHealthMe is studying from 2,213 Minipress users. Check the latest studies of Minipress.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

On Aug, 08, 2026

17 people who take Minipress and Restoril together, and have interactions are studied.

Minipress and Restoril drug interactions.

What are the common drug interactions of Minipress and Restoril, by gender? *:

female:

Vomiting
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Arthralgia (joint pain)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Fatigue (feeling of tiredness)
Fibromyalgia (a long-term condition which causes pain all over the body)
Joint crepitation
Joint stiffness
Muscle spasms (muscle contraction)
Night sweats (sweating in night)

male:

Blood triglycerides increased
Granulocytopenia (lack of granulocyte)
Hyperphagia (an abnormal appetite for food)
Loss of consciousness
Nausea (feeling of having an urge to vomit)
Retching (strong involuntary effort to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Weight increased
Back pain
Fatigue (feeling of tiredness)

What are the common drug interactions of Minipress and Restoril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Amino acid level decreased
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)

50-59:

Granulocytopenia (lack of granulocyte)
Blood cholesterol increased
Blood glucose increased
Blood triglycerides increased
Haematocrit decreased
Haemoglobin decreased
Overdose
Lymphocyte count increased
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Red blood cell count decreased

60+:

Vomiting
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Peptic ulcer
Ulcer
Anaemia (lack of blood)
Bacteraemia (presence of bacteria in the blood)
Candidiasis (candidiasis or thrush is a fungal infection)
Cellulitis (infection under the skin)
Difficulty in walking
Dry skin

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 29.41%
Stress And Anxiety: 3 people, 17.65%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 11.76%
Nausea (feeling of having an urge to vomit): 2 people, 11.76%
Joint Pain: 2 people, 11.76%
Sinus Disorder (disease of sinus): 1 person, 5.88%
Panic Disorder: 1 person, 5.88%
Pain: 1 person, 5.88%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 5.88%
Migraine (headache): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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