Minocin and Ambien drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Minocin (minocycline hydrochloride) and Ambien (zolpidem tartrate). Common drug interactions include mean cell volume decreased among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Minocin and Ambien. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Minocin?

Minocin has active ingredients of minocycline hydrochloride. It is often used in acne. eHealthMe is studying from 2,278 Minocin users. Check the latest studies of Minocin.

What is Ambien?

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 93,519 Ambien users. Check the latest studies of Ambien.

On Jul, 12, 2026

32 people who take Minocin and Ambien together, and have interactions are studied.

What are the common drug interactions of Minocin and Ambien, by gender? *:

female:

Mean cell volume decreased (less of the average red blood cell volume)
Neuropathy peripheral (surface nerve damage)
Productive cough
Proteinuria (presence of protein in the urine)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal hypertrophy (over growth of kidney)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection
Wheezing (a high-pitched whistling sound made while you breath)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

male:

Dehydration (dryness resulting from the removal of water)
Neutropenia (an abnormally low number of neutrophils)
Blood pressure decreased
Blood sodium decreased
Blood urea increased
Body temperature decreased
Body temperature increased
Dizziness
Fall
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

What are the common drug interactions of Minocin and Ambien, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Metal poisoning
Skin discolouration (change of skin colour)

20-29:

Abdominal pain lower
Alanine aminotransferase increased
Albumin urine present
Anxiety
Compulsive shopping
Constipation
Cough
Diarrhoea
Dysplasia (enlargement of an organ or tissue)
Eating disorder

30-39:

n/a

40-49:

Burning sensation
Cardiac disorder
Cardiac flutter (abnormal heart rhythm)
Cough
Decreased appetite
Diarrhoea
Drug ineffective
Feeling jittery
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Heart rate increased

50-59:

Fatigue (feeling of tiredness)
Anaemia (lack of blood)
Nausea (feeling of having an urge to vomit)
Febrile neutropenia (fever with reduced white blood cells)
Abdominal pain
Asthenia (weakness)
Back pain
Blood glucose increased
Chest pain
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

60+:

Dehydration (dryness resulting from the removal of water)
Chronic kidney disease
Aspartate aminotransferase increased
Band neutrophil percentage decreased
Blood pressure decreased
Blood sodium decreased
Blood urea increased
Body temperature decreased
Body temperature increased
Dizziness

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 6 people, 18.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.62%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 9.38%
Stress And Anxiety: 3 people, 9.38%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 9.38%
Pelvic Pain: 3 people, 9.38%
Panic Disorder: 3 people, 9.38%
Pain: 3 people, 9.38%
Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 3 people, 9.38%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 9.38%

* Approximation only. Some reports may have incomplete information.

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